Results for ERCC1

General Information

Gene ID 2067
Gene Symbol ERCC1
Gene Name excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Gene Type protein-coding
Cytoband 19q13.32
Ensembl ID ENSG00000012061
#miR regulators 4
Omim ID 126380 610758
Gene ontology GO:0051276: chromosome organization
GO:0000718: nucleotide-excision repair, DNA damage removal
GO:0000720: pyrimidine dimer repair by nucleotide-excision repair
GO:0001302: replicative cell aging
GO:0006281: DNA repair
GO:0006283: transcription-coupled nucleotide-excision repair
GO:0006289: nucleotide-excision repair
GO:0006295: nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296: nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006302: double-strand break repair
GO:0006310: DNA recombination
GO:0006312: mitotic recombination
GO:0006949: syncytium formation
GO:0006979: response to oxidative stress
GO:0007281: germ cell development
GO:0007283: spermatogenesis
GO:0007584: response to nutrient
GO:0043066: negative regulation of apoptotic process
GO:0008283: cell proliferation
GO:0008584: male gonad development
GO:0009650: UV protection
GO:0009744: response to sucrose stimulus
GO:0010165: response to X-ray
GO:0010259: multicellular organismal aging
GO:0032205: negative regulation of telomere maintenance
GO:0035166: post-embryonic hemopoiesis
GO:0035264: multicellular organism growth
GO:0045190: isotype switching
GO:0048477: oogenesis
GO:0048568: embryonic organ development
GO:0000109: nucleotide-excision repair complex
GO:0000784: nuclear chromosome, telomeric region
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005669: transcription factor TFIID complex
GO:0000014: single-stranded DNA endodeoxyribonuclease activity
GO:0005515: protein binding
GO:0001094: TFIID-class transcription factor binding
GO:0003684: damaged DNA binding
GO:0003697: single-stranded DNA binding
GO:0008022: protein C-terminus binding
GO:0017025: TBP-class protein binding
GO:0019904: protein domain specific binding
GO:0043566: structure-specific DNA binding
KEGG pathways 3420: Nucleotide excision repair

PubMed abstracts associated with ERCC1

PMID Title Tumor Value
21826087 Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy. yes yes
23098477 Association of four ERCC1 and ERCC2 SNPs with survival of bone tumour patients. yes yes
23317281 Glutathione S-transferase P1 and DNA polymorphisms influence response to chemotherapy and prognosis of bone tumors. yes yes
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