General Information
Gene ID | 2100 |
---|---|
Gene Symbol | ESR2 |
Gene Name | estrogen receptor 2 (ER beta) |
Gene Type | protein-coding |
Cytoband | 14q23.2 |
Ensembl ID | ENSG00000140009 |
#miR regulators | 3 |
Omim ID | 601663 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001541: ovarian follicle development GO:0001764: neuron migration GO:0007165: signal transduction GO:0006355: regulation of transcription, DNA-dependent GO:0006367: transcription initiation from RNA polymerase II promoter GO:0007267: cell-cell signaling GO:0007420: brain development GO:0010467: gene expression GO:0030308: negative regulation of cell growth GO:0030520: intracellular estrogen receptor signaling pathway GO:0043065: positive regulation of apoptotic process GO:0050680: negative regulation of epithelial cell proliferation GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity GO:0060065: uterus development GO:0060068: vagina development GO:0060740: prostate gland epithelium morphogenesis GO:0060743: epithelial cell maturation involved in prostate gland development GO:0060766: negative regulation of androgen receptor signaling pathway GO:1900116: extracellular negative regulation of signal transduction GO:0005739: mitochondrion GO:0005576: extracellular region GO:0005634: nucleus GO:0005654: nucleoplasm GO:0005515: protein binding GO:0001046: core promoter sequence-specific DNA binding GO:0003677: DNA binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0004879: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0003707: steroid hormone receptor activity GO:0003713: transcription coactivator activity GO:0005496: steroid binding GO:0008270: zinc ion binding GO:0019899: enzyme binding GO:0030284: estrogen receptor activity GO:0034056: estrogen response element binding GO:0048019: receptor antagonist activity |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
10352100 | Expression and localization of estrogen receptor-beta in murine and human bone. | no | no |
18081879 | Sex steroid receptors expression and hormone-induced cell proliferation in human osteosarcoma. | yes | no |
19347870 | Down-regulation of epidermal growth factor receptor induced by estrogens and phytoestrogens promotes the differentiation of U2OS human osteosarcoma cells. | no | no |
title | all | all |