Results for EZH2

General Information

Gene ID 2146
Gene Symbol EZH2
Gene Name enhancer of zeste homolog 2 (Drosophila)
Gene Type protein-coding
Cytoband 7q35-q36
Ensembl ID ENSG00000106462
#miR regulators 5
Omim ID 277590 601573
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0006325: chromatin organization
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0010718: positive regulation of epithelial to mesenchymal transition
GO:0014013: regulation of gliogenesis
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0021695: cerebellar cortex development
GO:0032320: positive regulation of Ras GTPase activity
GO:0034244: negative regulation of transcription elongation from RNA polymerase II promoter
GO:0042127: regulation of cell proliferation
GO:0043406: positive regulation of MAP kinase activity
GO:0045605: negative regulation of epidermal cell differentiation
GO:0045814: negative regulation of gene expression, epigenetic
GO:0048387: negative regulation of retinoic acid receptor signaling pathway
GO:0051154: negative regulation of striated muscle cell differentiation
GO:0070314: G1 to G0 transition
GO:0070734: histone H3-K27 methylation
GO:0071902: positive regulation of protein serine/threonine kinase activity
GO:2000134: negative regulation of G1/S transition of mitotic cell cycle
GO:0035098: ESC/E(Z) complex
GO:0045120: pronucleus
GO:0005515: protein binding
GO:0001047: core promoter binding
GO:0003677: DNA binding
GO:0003682: chromatin binding
GO:0003723: RNA binding
GO:0018024: histone-lysine N-methyltransferase activity
GO:0042054: histone methyltransferase activity
GO:0043565: sequence-specific DNA binding
KEGG pathways ---

PubMed abstracts associated with EZH2

PMID Title Tumor Value
20127006 The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth. yes no
title all all