General Information
Gene ID | 2150 |
---|---|
Gene Symbol | F2RL1 |
Gene Name | coagulation factor II (thrombin) receptor-like 1 |
Gene Type | protein-coding |
Cytoband | 5q13 |
Ensembl ID | ENSG00000164251 |
#miR regulators | 11 |
Omim ID | 600933 |
Gene ontology |
GO:0002286: T cell activation involved in immune response GO:0002690: positive regulation of leukocyte chemotaxis GO:0002741: positive regulation of cytokine secretion involved in immune response GO:0003104: positive regulation of glomerular filtration GO:0007596: blood coagulation GO:0006954: inflammatory response GO:0007186: G-protein coupled receptor signaling pathway GO:0007204: elevation of cytosolic calcium ion concentration GO:0045909: positive regulation of vasodilation GO:0010804: negative regulation of tumor necrosis factor-mediated signaling pathway GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade GO:0030193: regulation of blood coagulation GO:0030335: positive regulation of cell migration GO:0030836: positive regulation of actin filament depolymerization GO:0031274: positive regulation of pseudopodium assembly GO:0032930: positive regulation of superoxide anion generation GO:0034137: positive regulation of toll-like receptor 2 signaling pathway GO:0034140: negative regulation of toll-like receptor 3 signaling pathway GO:0034141: positive regulation of toll-like receptor 3 signaling pathway GO:0034145: positive regulation of toll-like receptor 4 signaling pathway GO:0035025: positive regulation of Rho protein signal transduction GO:0035926: chemokine (C-C motif) ligand 2 secretion GO:0042119: neutrophil activation GO:0043122: regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043311: positive regulation of eosinophil degranulation GO:0045087: innate immune response GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0046328: regulation of JNK cascade GO:0046329: negative regulation of JNK cascade GO:0046330: positive regulation of JNK cascade GO:0050702: interleukin-1 beta secretion GO:0050900: leukocyte migration GO:0050921: positive regulation of chemotaxis GO:0050927: positive regulation of positive chemotaxis GO:0051607: defense response to virus GO:0060100: positive regulation of phagocytosis, engulfment GO:0061028: establishment of endothelial barrier GO:0070374: positive regulation of ERK1 and ERK2 cascade GO:0070661: leukocyte proliferation GO:0070963: positive regulation of neutrophil mediated killing of gram-negative bacterium GO:0072608: interleukin-10 secretion GO:0072643: interferon-gamma secretion GO:0090195: chemokine secretion GO:0090198: negative regulation of chemokine secretion GO:0097029: mature dendritic cell differentiation GO:1900135: positive regulation of renin secretion into blood stream GO:2000484: positive regulation of interleukin-8 secretion GO:2000778: positive regulation of interleukin-6 secretion GO:0005886: plasma membrane GO:0005887: integral to plasma membrane GO:0005794: Golgi apparatus GO:0031143: pseudopodium GO:0005515: protein binding GO:0001965: G-protein alpha-subunit binding GO:0005102: receptor binding GO:0004872: receptor activity GO:0004930: G-protein coupled receptor activity GO:0015057: thrombin receptor activity GO:0031681: G-protein beta-subunit binding |
KEGG pathways |
4080: Neuroactive ligand-receptor interaction 5143: African trypanosomiasis |
PMID | Title | Tumor | Value |
---|---|---|---|
17509570 | Osteosarcoma cell-calcium signaling through tissue factor-factor VIIa complex and factor Xa. | no | no |
20563836 | Expression of proteinase-activated receptor 1-4 (PAR 1-4) in human cancer. | yes | no |
title | all | all |