Results for F2RL1

General Information

Gene ID 2150
Gene Symbol F2RL1
Gene Name coagulation factor II (thrombin) receptor-like 1
Gene Type protein-coding
Cytoband 5q13
Ensembl ID ENSG00000164251
#miR regulators 11
Omim ID 600933
Gene ontology GO:0002286: T cell activation involved in immune response
GO:0002690: positive regulation of leukocyte chemotaxis
GO:0002741: positive regulation of cytokine secretion involved in immune response
GO:0003104: positive regulation of glomerular filtration
GO:0007596: blood coagulation
GO:0006954: inflammatory response
GO:0007186: G-protein coupled receptor signaling pathway
GO:0007204: elevation of cytosolic calcium ion concentration
GO:0045909: positive regulation of vasodilation
GO:0010804: negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade
GO:0030193: regulation of blood coagulation
GO:0030335: positive regulation of cell migration
GO:0030836: positive regulation of actin filament depolymerization
GO:0031274: positive regulation of pseudopodium assembly
GO:0032930: positive regulation of superoxide anion generation
GO:0034137: positive regulation of toll-like receptor 2 signaling pathway
GO:0034140: negative regulation of toll-like receptor 3 signaling pathway
GO:0034141: positive regulation of toll-like receptor 3 signaling pathway
GO:0034145: positive regulation of toll-like receptor 4 signaling pathway
GO:0035025: positive regulation of Rho protein signal transduction
GO:0035926: chemokine (C-C motif) ligand 2 secretion
GO:0042119: neutrophil activation
GO:0043122: regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043311: positive regulation of eosinophil degranulation
GO:0045087: innate immune response
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0046328: regulation of JNK cascade
GO:0046329: negative regulation of JNK cascade
GO:0046330: positive regulation of JNK cascade
GO:0050702: interleukin-1 beta secretion
GO:0050900: leukocyte migration
GO:0050921: positive regulation of chemotaxis
GO:0050927: positive regulation of positive chemotaxis
GO:0051607: defense response to virus
GO:0060100: positive regulation of phagocytosis, engulfment
GO:0061028: establishment of endothelial barrier
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0070661: leukocyte proliferation
GO:0070963: positive regulation of neutrophil mediated killing of gram-negative bacterium
GO:0072608: interleukin-10 secretion
GO:0072643: interferon-gamma secretion
GO:0090195: chemokine secretion
GO:0090198: negative regulation of chemokine secretion
GO:0097029: mature dendritic cell differentiation
GO:1900135: positive regulation of renin secretion into blood stream
GO:2000484: positive regulation of interleukin-8 secretion
GO:2000778: positive regulation of interleukin-6 secretion
GO:0005886: plasma membrane
GO:0005887: integral to plasma membrane
GO:0005794: Golgi apparatus
GO:0031143: pseudopodium
GO:0005515: protein binding
GO:0001965: G-protein alpha-subunit binding
GO:0005102: receptor binding
GO:0004872: receptor activity
GO:0004930: G-protein coupled receptor activity
GO:0015057: thrombin receptor activity
GO:0031681: G-protein beta-subunit binding
KEGG pathways 4080: Neuroactive ligand-receptor interaction
5143: African trypanosomiasis

PubMed abstracts associated with F2RL1

PMID Title Tumor Value
17509570 Osteosarcoma cell-calcium signaling through tissue factor-factor VIIa complex and factor Xa. no no
20563836 Expression of proteinase-activated receptor 1-4 (PAR 1-4) in human cancer. yes no
title all all