Results for FASN

General Information

Gene ID 2194
Gene Symbol FASN
Gene Name fatty acid synthase
Gene Type protein-coding
Cytoband 17q25
Ensembl ID ENSG00000169710
#miR regulators 6
Omim ID 600212
Gene ontology GO:0006084: acetyl-CoA metabolic process
GO:0006112: energy reserve metabolic process
GO:0006631: fatty acid metabolic process
GO:0006633: fatty acid biosynthetic process
GO:0006766: vitamin metabolic process
GO:0006767: water-soluble vitamin metabolic process
GO:0015939: pantothenate metabolic process
GO:0019432: triglyceride biosynthetic process
GO:0031325: positive regulation of cellular metabolic process
GO:0035338: long-chain fatty-acyl-CoA biosynthetic process
GO:0044255: cellular lipid metabolic process
GO:0044281: small molecule metabolic process
GO:0071353: cellular response to interleukin-4
GO:0005886: plasma membrane
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005737: cytoplasm
GO:0005794: Golgi apparatus
GO:0042470: melanosome
GO:0042587: glycogen granule
GO:0005515: protein binding
GO:0004312: fatty acid synthase activity
GO:0004313: [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314: [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315: 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0004316: 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0004317: 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
GO:0004319: enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
GO:0004320: oleoyl-[acyl-carrier-protein] hydrolase activity
GO:0008144: drug binding
GO:0008270: zinc ion binding
GO:0016295: myristoyl-[acyl-carrier-protein] hydrolase activity
GO:0016296: palmitoyl-[acyl-carrier-protein] hydrolase activity
GO:0042803: protein homodimerization activity
GO:0047117: enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity
GO:0047451: 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO:0070402: NADPH binding
KEGG pathways 61: Fatty acid biosynthesis
1100: Metabolic pathways
4910: Insulin signaling pathway

PubMed abstracts associated with FASN

PMID Title Tumor Value
22771636 Inhibition of fatty acid synthase supresses osteosarcoma cell invasion and migration. yes no
title all all