General Information
Gene ID | 2194 |
---|---|
Gene Symbol | FASN |
Gene Name | fatty acid synthase |
Gene Type | protein-coding |
Cytoband | 17q25 |
Ensembl ID | ENSG00000169710 |
#miR regulators | 6 |
Omim ID | 600212 |
Gene ontology |
GO:0006084: acetyl-CoA metabolic process GO:0006112: energy reserve metabolic process GO:0006631: fatty acid metabolic process GO:0006633: fatty acid biosynthetic process GO:0006766: vitamin metabolic process GO:0006767: water-soluble vitamin metabolic process GO:0015939: pantothenate metabolic process GO:0019432: triglyceride biosynthetic process GO:0031325: positive regulation of cellular metabolic process GO:0035338: long-chain fatty-acyl-CoA biosynthetic process GO:0044255: cellular lipid metabolic process GO:0044281: small molecule metabolic process GO:0071353: cellular response to interleukin-4 GO:0005886: plasma membrane GO:0005739: mitochondrion GO:0005829: cytosol GO:0005737: cytoplasm GO:0005794: Golgi apparatus GO:0042470: melanosome GO:0042587: glycogen granule GO:0005515: protein binding GO:0004312: fatty acid synthase activity GO:0004313: [acyl-carrier-protein] S-acetyltransferase activity GO:0004314: [acyl-carrier-protein] S-malonyltransferase activity GO:0004315: 3-oxoacyl-[acyl-carrier-protein] synthase activity GO:0004316: 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004317: 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity GO:0004319: enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity GO:0004320: oleoyl-[acyl-carrier-protein] hydrolase activity GO:0008144: drug binding GO:0008270: zinc ion binding GO:0016295: myristoyl-[acyl-carrier-protein] hydrolase activity GO:0016296: palmitoyl-[acyl-carrier-protein] hydrolase activity GO:0042803: protein homodimerization activity GO:0047117: enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity GO:0047451: 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity GO:0070402: NADPH binding |
KEGG pathways |
61: Fatty acid biosynthesis 1100: Metabolic pathways 4910: Insulin signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
22771636 | Inhibition of fatty acid synthase supresses osteosarcoma cell invasion and migration. | yes | no |
title | all | all |