Results for FGF1

General Information

Gene ID 2246
Gene Symbol FGF1
Gene Name fibroblast growth factor 1 (acidic)
Gene Type protein-coding
Cytoband 5q31
Ensembl ID ENSG00000113578
#miR regulators 13
Omim ID 131220
Gene ontology GO:0001525: angiogenesis
GO:0001759: organ induction
GO:0001934: positive regulation of protein phosphorylation
GO:0007165: signal transduction
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007275: multicellular organismal development
GO:0009653: anatomical structure morphogenesis
GO:0008284: positive regulation of cell proliferation
GO:0008286: insulin receptor signaling pathway
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0010740: positive regulation of intracellular protein kinase cascade
GO:0048015: phosphatidylinositol-mediated signaling
GO:0030324: lung development
GO:0030335: positive regulation of cell migration
GO:0034605: cellular response to heat
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0045087: innate immune response
GO:0045542: positive regulation of cholesterol biosynthetic process
GO:0045766: positive regulation of angiogenesis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0050679: positive regulation of epithelial cell proliferation
GO:0051781: positive regulation of cell division
GO:0060681: branch elongation involved in ureteric bud branching
GO:0072163: mesonephric epithelium development
GO:0005576: extracellular region
GO:0005829: cytosol
GO:0005578: proteinaceous extracellular matrix
GO:0005615: extracellular space
GO:0005730: nucleolus
GO:0005938: cell cortex
GO:0005515: protein binding
GO:0005104: fibroblast growth factor receptor binding
GO:0008083: growth factor activity
GO:0008201: heparin binding
GO:0030544: Hsp70 protein binding
GO:0044548: S100 protein binding
KEGG pathways 4010: MAPK signaling pathway
4810: Regulation of actin cytoskeleton
5200: Pathways in cancer
5218: Melanoma

PubMed abstracts associated with FGF1

PMID Title Tumor Value
1586971 Roles of various growth factors in growth of human osteosarcoma cells which can grow in protein-free medium. no no
10896792 The regulation of PGE(2) biosynthesis in MG-63 osteosarcoma cells by IL-1 and FGF is cell density-dependent. no no
14598359 Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. yes yes
20027339 Endostatin, placental growth factor, and fibroblast growth factors-1 and -2 in the sera of patients with primary osteosarcomas. yes no
21375766 RNAi-mediated knockdown of cyclooxygenase2 inhibits the growth, invasion and migration of SaOS2 human osteosarcoma cells: a case control study. no no
22009965 Expression of b-FGF and endostatin and their clinical significance in human osteosarcoma. yes yes
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