General Information
Gene ID | 2263 |
---|---|
Gene Symbol | FGFR2 |
Gene Name | fibroblast growth factor receptor 2 |
Gene Type | protein-coding |
Cytoband | 10q26 |
Ensembl ID | ENSG00000066468 |
#miR regulators | 13 |
Omim ID | 101200 101400 101600 123150 123500 123790 149730 176943 207410 609579 613659 614592 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001525: angiogenesis GO:0001657: ureteric bud development GO:0001701: in utero embryonic development GO:0002053: positive regulation of mesenchymal cell proliferation GO:0003148: outflow tract septum morphogenesis GO:0003149: membranous septum morphogenesis GO:0006915: apoptotic process GO:0007173: epidermal growth factor receptor signaling pathway GO:0007267: cell-cell signaling GO:0009880: embryonic pattern specification GO:0009887: organ morphogenesis GO:0007409: axonogenesis GO:0007528: neuromuscular junction development GO:0008284: positive regulation of cell proliferation GO:0008285: negative regulation of cell proliferation GO:0008286: insulin receptor signaling pathway GO:0008543: fibroblast growth factor receptor signaling pathway GO:0008589: regulation of smoothened signaling pathway GO:0009791: post-embryonic development GO:0010453: regulation of cell fate commitment GO:0010518: positive regulation of phospholipase activity GO:0016331: morphogenesis of embryonic epithelium GO:0018108: peptidyl-tyrosine phosphorylation GO:0048015: phosphatidylinositol-mediated signaling GO:0021769: orbitofrontal cortex development GO:0021847: ventricular zone neuroblast division GO:0021860: pyramidal neuron development GO:0022612: gland morphogenesis GO:0030177: positive regulation of Wnt receptor signaling pathway GO:0030282: bone mineralization GO:0030324: lung development GO:0030855: epithelial cell differentiation GO:0030901: midbrain development GO:0030916: otic vesicle formation GO:0031069: hair follicle morphogenesis GO:0032808: lacrimal gland development GO:0033688: regulation of osteoblast proliferation GO:0035264: multicellular organism growth GO:0035265: organ growth GO:0035602: fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow GO:0035603: fibroblast growth factor receptor signaling pathway involved in hemopoiesis GO:0035604: fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow GO:0035607: fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development GO:0038095: Fc-epsilon receptor signaling pathway GO:0040014: regulation of multicellular organism growth GO:0040036: regulation of fibroblast growth factor receptor signaling pathway GO:0042472: inner ear morphogenesis GO:0042476: odontogenesis GO:0043410: positive regulation of MAPK cascade GO:0045087: innate immune response GO:0045165: cell fate commitment GO:0045667: regulation of osteoblast differentiation GO:0045787: positive regulation of cell cycle GO:0045839: negative regulation of mitosis GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0046777: protein autophosphorylation GO:0048011: neurotrophin TRK receptor signaling pathway GO:0048286: lung alveolus development GO:0048489: synaptic vesicle transport GO:0048557: embryonic digestive tract morphogenesis GO:0048562: embryonic organ morphogenesis GO:0048565: digestive tract development GO:0048568: embryonic organ development GO:0048608: reproductive structure development GO:0048701: embryonic cranial skeleton morphogenesis GO:0048705: skeletal system morphogenesis GO:0048730: epidermis morphogenesis GO:0048755: branching morphogenesis of a nerve GO:0048762: mesenchymal cell differentiation GO:0050679: positive regulation of epithelial cell proliferation GO:0051150: regulation of smooth muscle cell differentiation GO:0051781: positive regulation of cell division GO:0055010: ventricular cardiac muscle tissue morphogenesis GO:0060045: positive regulation of cardiac muscle cell proliferation GO:0060174: limb bud formation GO:0060348: bone development GO:0060349: bone morphogenesis GO:0060365: coronal suture morphogenesis GO:0060442: branching involved in prostate gland morphogenesis GO:0060445: branching involved in salivary gland morphogenesis GO:0060449: bud elongation involved in lung branching GO:0060463: lung lobe morphogenesis GO:0060484: lung-associated mesenchyme development GO:0060501: positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060512: prostate gland morphogenesis GO:0060523: prostate epithelial cord elongation GO:0060527: prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060529: squamous basal epithelial stem cell differentiation involved in prostate gland acinus development GO:0060595: fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060601: lateral sprouting from an epithelium GO:0060615: mammary gland bud formation GO:0060664: epithelial cell proliferation involved in salivary gland morphogenesis GO:0060667: branch elongation involved in salivary gland morphogenesis GO:0060670: branching involved in labyrinthine layer morphogenesis GO:0060687: regulation of branching involved in prostate gland morphogenesis GO:0060688: regulation of morphogenesis of a branching structure GO:0060915: mesenchymal cell differentiation involved in lung development GO:0060916: mesenchymal cell proliferation involved in lung development GO:0061031: endodermal digestive tract morphogenesis GO:0070307: lens fiber cell development GO:0070372: regulation of ERK1 and ERK2 cascade GO:0070374: positive regulation of ERK1 and ERK2 cascade GO:0090263: positive regulation of canonical Wnt receptor signaling pathway GO:0005886: plasma membrane GO:0016021: integral to membrane GO:0016020: membrane GO:0005576: extracellular region GO:0005887: integral to plasma membrane GO:0005634: nucleus GO:0005737: cytoplasm GO:0005794: Golgi apparatus GO:0005938: cell cortex GO:0009986: cell surface GO:0016023: cytoplasmic membrane-bounded vesicle GO:0031012: extracellular matrix GO:0060076: excitatory synapse GO:0005515: protein binding GO:0004713: protein tyrosine kinase activity GO:0005007: fibroblast growth factor-activated receptor activity GO:0005524: ATP binding GO:0008201: heparin binding GO:0042802: identical protein binding GO:0017134: fibroblast growth factor binding GO:0042803: protein homodimerization activity |
KEGG pathways |
4010: MAPK signaling pathway 4144: Endocytosis 4810: Regulation of actin cytoskeleton 5200: Pathways in cancer 5215: Prostate cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
11874241 | Regulation of fibroblast growth factor 2 and fibroblast growth factor receptors by transforming growth factor beta in human osteoblastic MG-63 cells. | no | no |
15796961 | Allelic loss at 10q26 in osteosarcoma in the region of the BUB3 and FGFR2 genes. | yes | no |
title | all | all |