Results for FGFR2

General Information

Gene ID 2263
Gene Symbol FGFR2
Gene Name fibroblast growth factor receptor 2
Gene Type protein-coding
Cytoband 10q26
Ensembl ID ENSG00000066468
#miR regulators 13
Omim ID 101200 101400 101600 123150 123500 123790 149730 176943 207410 609579 613659 614592
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001525: angiogenesis
GO:0001657: ureteric bud development
GO:0001701: in utero embryonic development
GO:0002053: positive regulation of mesenchymal cell proliferation
GO:0003148: outflow tract septum morphogenesis
GO:0003149: membranous septum morphogenesis
GO:0006915: apoptotic process
GO:0007173: epidermal growth factor receptor signaling pathway
GO:0007267: cell-cell signaling
GO:0009880: embryonic pattern specification
GO:0009887: organ morphogenesis
GO:0007409: axonogenesis
GO:0007528: neuromuscular junction development
GO:0008284: positive regulation of cell proliferation
GO:0008285: negative regulation of cell proliferation
GO:0008286: insulin receptor signaling pathway
GO:0008543: fibroblast growth factor receptor signaling pathway
GO:0008589: regulation of smoothened signaling pathway
GO:0009791: post-embryonic development
GO:0010453: regulation of cell fate commitment
GO:0010518: positive regulation of phospholipase activity
GO:0016331: morphogenesis of embryonic epithelium
GO:0018108: peptidyl-tyrosine phosphorylation
GO:0048015: phosphatidylinositol-mediated signaling
GO:0021769: orbitofrontal cortex development
GO:0021847: ventricular zone neuroblast division
GO:0021860: pyramidal neuron development
GO:0022612: gland morphogenesis
GO:0030177: positive regulation of Wnt receptor signaling pathway
GO:0030282: bone mineralization
GO:0030324: lung development
GO:0030855: epithelial cell differentiation
GO:0030901: midbrain development
GO:0030916: otic vesicle formation
GO:0031069: hair follicle morphogenesis
GO:0032808: lacrimal gland development
GO:0033688: regulation of osteoblast proliferation
GO:0035264: multicellular organism growth
GO:0035265: organ growth
GO:0035602: fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow
GO:0035603: fibroblast growth factor receptor signaling pathway involved in hemopoiesis
GO:0035604: fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
GO:0035607: fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0040014: regulation of multicellular organism growth
GO:0040036: regulation of fibroblast growth factor receptor signaling pathway
GO:0042472: inner ear morphogenesis
GO:0042476: odontogenesis
GO:0043410: positive regulation of MAPK cascade
GO:0045087: innate immune response
GO:0045165: cell fate commitment
GO:0045667: regulation of osteoblast differentiation
GO:0045787: positive regulation of cell cycle
GO:0045839: negative regulation of mitosis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0046777: protein autophosphorylation
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0048286: lung alveolus development
GO:0048489: synaptic vesicle transport
GO:0048557: embryonic digestive tract morphogenesis
GO:0048562: embryonic organ morphogenesis
GO:0048565: digestive tract development
GO:0048568: embryonic organ development
GO:0048608: reproductive structure development
GO:0048701: embryonic cranial skeleton morphogenesis
GO:0048705: skeletal system morphogenesis
GO:0048730: epidermis morphogenesis
GO:0048755: branching morphogenesis of a nerve
GO:0048762: mesenchymal cell differentiation
GO:0050679: positive regulation of epithelial cell proliferation
GO:0051150: regulation of smooth muscle cell differentiation
GO:0051781: positive regulation of cell division
GO:0055010: ventricular cardiac muscle tissue morphogenesis
GO:0060045: positive regulation of cardiac muscle cell proliferation
GO:0060174: limb bud formation
GO:0060348: bone development
GO:0060349: bone morphogenesis
GO:0060365: coronal suture morphogenesis
GO:0060442: branching involved in prostate gland morphogenesis
GO:0060445: branching involved in salivary gland morphogenesis
GO:0060449: bud elongation involved in lung branching
GO:0060463: lung lobe morphogenesis
GO:0060484: lung-associated mesenchyme development
GO:0060501: positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060512: prostate gland morphogenesis
GO:0060523: prostate epithelial cord elongation
GO:0060527: prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060529: squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:0060595: fibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0060601: lateral sprouting from an epithelium
GO:0060615: mammary gland bud formation
GO:0060664: epithelial cell proliferation involved in salivary gland morphogenesis
GO:0060667: branch elongation involved in salivary gland morphogenesis
GO:0060670: branching involved in labyrinthine layer morphogenesis
GO:0060687: regulation of branching involved in prostate gland morphogenesis
GO:0060688: regulation of morphogenesis of a branching structure
GO:0060915: mesenchymal cell differentiation involved in lung development
GO:0060916: mesenchymal cell proliferation involved in lung development
GO:0061031: endodermal digestive tract morphogenesis
GO:0070307: lens fiber cell development
GO:0070372: regulation of ERK1 and ERK2 cascade
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0090263: positive regulation of canonical Wnt receptor signaling pathway
GO:0005886: plasma membrane
GO:0016021: integral to membrane
GO:0016020: membrane
GO:0005576: extracellular region
GO:0005887: integral to plasma membrane
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005794: Golgi apparatus
GO:0005938: cell cortex
GO:0009986: cell surface
GO:0016023: cytoplasmic membrane-bounded vesicle
GO:0031012: extracellular matrix
GO:0060076: excitatory synapse
GO:0005515: protein binding
GO:0004713: protein tyrosine kinase activity
GO:0005007: fibroblast growth factor-activated receptor activity
GO:0005524: ATP binding
GO:0008201: heparin binding
GO:0042802: identical protein binding
GO:0017134: fibroblast growth factor binding
GO:0042803: protein homodimerization activity
KEGG pathways 4010: MAPK signaling pathway
4144: Endocytosis
4810: Regulation of actin cytoskeleton
5200: Pathways in cancer
5215: Prostate cancer

PubMed abstracts associated with FGFR2

PMID Title Tumor Value
11874241 Regulation of fibroblast growth factor 2 and fibroblast growth factor receptors by transforming growth factor beta in human osteoblastic MG-63 cells. no no
15796961 Allelic loss at 10q26 in osteosarcoma in the region of the BUB3 and FGFR2 genes. yes no
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