Results for KDM1A

General Information

Gene ID 23028
Gene Symbol KDM1A
Gene Name lysine (K)-specific demethylase 1A
Gene Type protein-coding
Cytoband 1p36.12
Ensembl ID ENSG00000004487
#miR regulators 1
Omim ID 609132
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001701: in utero embryonic development
GO:0007596: blood coagulation
GO:0006351: transcription, DNA-dependent
GO:0006357: regulation of transcription from RNA polymerase II promoter
GO:0006482: protein demethylation
GO:0008283: cell proliferation
GO:0010725: regulation of primitive erythrocyte differentiation
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0046886: positive regulation of hormone biosynthetic process
GO:0021983: pituitary gland development
GO:0030851: granulocyte differentiation
GO:0032091: negative regulation of protein binding
GO:0033169: histone H3-K9 demethylation
GO:0034720: histone H3-K4 demethylation
GO:0043392: negative regulation of DNA binding
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043518: negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045648: positive regulation of erythrocyte differentiation
GO:0045654: positive regulation of megakaryocyte differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051572: negative regulation of histone H3-K4 methylation
GO:0051573: negative regulation of histone H3-K9 methylation
GO:0055001: muscle cell development
GO:1902166: negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:2000179: positive regulation of neural precursor cell proliferation
GO:2000648: positive regulation of stem cell proliferation
GO:0000790: nuclear chromatin
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0001085: RNA polymerase II transcription factor binding
GO:0002039: p53 binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0016491: oxidoreductase activity
GO:0008134: transcription factor binding
GO:0044212: transcription regulatory region DNA binding
GO:0019899: enzyme binding
GO:0030374: ligand-dependent nuclear receptor transcription coactivator activity
GO:0032451: demethylase activity
GO:0032452: histone demethylase activity
GO:0032453: histone demethylase activity (H3-K4 specific)
GO:0032454: histone demethylase activity (H3-K9 specific)
GO:0034648: histone demethylase activity (H3-dimethyl-K4 specific)
GO:0043426: MRF binding
GO:0050660: flavin adenine dinucleotide binding
GO:0050681: androgen receptor binding
KEGG pathways ---

PubMed abstracts associated with KDM1A

PMID Title Tumor Value
22245111 Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma. yes no
title all all