Results for PLCB1

General Information

Gene ID 23236
Gene Symbol PLCB1
Gene Name phospholipase C, beta 1 (phosphoinositide-specific)
Gene Type protein-coding
Cytoband 20p12
Ensembl ID ENSG00000182621
#miR regulators 16
Omim ID 607120 613722
Gene ontology GO:0000086: G2/M transition of mitotic cell cycle
GO:0007165: signal transduction
GO:0035556: intracellular signal transduction
GO:0007213: G-protein coupled acetylcholine receptor signaling pathway
GO:0007215: glutamate receptor signaling pathway
GO:0007268: synaptic transmission
GO:0007613: memory
GO:0008277: regulation of G-protein coupled receptor protein signaling pathway
GO:0016042: lipid catabolic process
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0021987: cerebral cortex development
GO:0032735: positive regulation of interleukin-12 production
GO:0035722: interleukin-12-mediated signaling pathway
GO:0035723: interleukin-15-mediated signaling pathway
GO:0040019: positive regulation of embryonic development
GO:0043547: positive regulation of GTPase activity
GO:0043647: inositol phosphate metabolic process
GO:0044281: small molecule metabolic process
GO:0045444: fat cell differentiation
GO:0045663: positive regulation of myoblast differentiation
GO:0046330: positive regulation of JNK cascade
GO:0046488: phosphatidylinositol metabolic process
GO:0048009: insulin-like growth factor receptor signaling pathway
GO:0048639: positive regulation of developmental growth
GO:0060466: activation of meiosis involved in egg activation
GO:0070498: interleukin-1-mediated signaling pathway
GO:0080154: regulation of fertilization
GO:1900087: positive regulation of G1/S transition of mitotic cell cycle
GO:2000344: positive regulation of acrosome reaction
GO:2000438: negative regulation of monocyte extravasation
GO:2000560: positive regulation of CD24 biosynthetic process
GO:0000790: nuclear chromatin
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0016607: nuclear speck
GO:0031965: nuclear membrane
GO:0005509: calcium ion binding
GO:0005521: lamin binding
GO:0004435: phosphatidylinositol phospholipase C activity
GO:0004871: signal transducer activity
GO:0005096: GTPase activator activity
GO:0005516: calmodulin binding
GO:0005546: phosphatidylinositol-4,5-bisphosphate binding
GO:0019899: enzyme binding
GO:0042803: protein homodimerization activity
KEGG pathways 562: Inositol phosphate metabolism
1100: Metabolic pathways
4020: Calcium signaling pathway
4062: Chemokine signaling pathway
4070: Phosphatidylinositol signaling system
4270: Vascular smooth muscle contraction
4310: Wnt signaling pathway
4540: Gap junction
4720: Long-term potentiation
4730: Long-term depression
4912: GnRH signaling pathway
4916: Melanogenesis
4970: Salivary secretion
4971: Gastric acid secretion
4972: Pancreatic secretion
5010: Alzheimer's disease
5016: Huntington's disease
5142: Chagas disease (American trypanosomiasis)
5143: African trypanosomiasis
5146: Amoebiasis

PubMed abstracts associated with PLCB1

PMID Title Tumor Value
8276785 Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells. no no
title all all