General Information
Gene ID | 23236 |
---|---|
Gene Symbol | PLCB1 |
Gene Name | phospholipase C, beta 1 (phosphoinositide-specific) |
Gene Type | protein-coding |
Cytoband | 20p12 |
Ensembl ID | ENSG00000182621 |
#miR regulators | 16 |
Omim ID | 607120 613722 |
Gene ontology |
GO:0000086: G2/M transition of mitotic cell cycle GO:0007165: signal transduction GO:0035556: intracellular signal transduction GO:0007213: G-protein coupled acetylcholine receptor signaling pathway GO:0007215: glutamate receptor signaling pathway GO:0007268: synaptic transmission GO:0007613: memory GO:0008277: regulation of G-protein coupled receptor protein signaling pathway GO:0016042: lipid catabolic process GO:0045893: positive regulation of transcription, DNA-dependent GO:0045892: negative regulation of transcription, DNA-dependent GO:0021987: cerebral cortex development GO:0032735: positive regulation of interleukin-12 production GO:0035722: interleukin-12-mediated signaling pathway GO:0035723: interleukin-15-mediated signaling pathway GO:0040019: positive regulation of embryonic development GO:0043547: positive regulation of GTPase activity GO:0043647: inositol phosphate metabolic process GO:0044281: small molecule metabolic process GO:0045444: fat cell differentiation GO:0045663: positive regulation of myoblast differentiation GO:0046330: positive regulation of JNK cascade GO:0046488: phosphatidylinositol metabolic process GO:0048009: insulin-like growth factor receptor signaling pathway GO:0048639: positive regulation of developmental growth GO:0060466: activation of meiosis involved in egg activation GO:0070498: interleukin-1-mediated signaling pathway GO:0080154: regulation of fertilization GO:1900087: positive regulation of G1/S transition of mitotic cell cycle GO:2000344: positive regulation of acrosome reaction GO:2000438: negative regulation of monocyte extravasation GO:2000560: positive regulation of CD24 biosynthetic process GO:0000790: nuclear chromatin GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0016607: nuclear speck GO:0031965: nuclear membrane GO:0005509: calcium ion binding GO:0005521: lamin binding GO:0004435: phosphatidylinositol phospholipase C activity GO:0004871: signal transducer activity GO:0005096: GTPase activator activity GO:0005516: calmodulin binding GO:0005546: phosphatidylinositol-4,5-bisphosphate binding GO:0019899: enzyme binding GO:0042803: protein homodimerization activity |
KEGG pathways |
562: Inositol phosphate metabolism 1100: Metabolic pathways 4020: Calcium signaling pathway 4062: Chemokine signaling pathway 4070: Phosphatidylinositol signaling system 4270: Vascular smooth muscle contraction 4310: Wnt signaling pathway 4540: Gap junction 4720: Long-term potentiation 4730: Long-term depression 4912: GnRH signaling pathway 4916: Melanogenesis 4970: Salivary secretion 4971: Gastric acid secretion 4972: Pancreatic secretion 5010: Alzheimer's disease 5016: Huntington's disease 5142: Chagas disease (American trypanosomiasis) 5143: African trypanosomiasis 5146: Amoebiasis |
PMID | Title | Tumor | Value |
---|---|---|---|
8276785 | Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells. | no | no |
title | all | all |