General Information
| Gene ID | 2339 |
|---|---|
| Gene Symbol | FNTA |
| Gene Name | farnesyltransferase, CAAX box, alpha |
| Gene Type | protein-coding |
| Cytoband | 8p11 |
| Ensembl ID | ENSG00000168522 |
| #miR regulators | 7 |
| Omim ID | 134635 |
| Gene ontology |
GO:0006915: apoptotic process GO:0018343: protein farnesylation GO:0018344: protein geranylgeranylation GO:0006921: cellular component disassembly involved in execution phase of apoptosis GO:0007179: transforming growth factor beta receptor signaling pathway GO:0007603: phototransduction, visible light GO:0016056: rhodopsin mediated signaling pathway GO:0022400: regulation of rhodopsin mediated signaling pathway GO:0045213: neurotransmitter receptor metabolic process GO:0090044: positive regulation of tubulin deacetylation GO:0090045: positive regulation of deacetylase activity GO:0005829: cytosol GO:0005737: cytoplasm GO:0005875: microtubule associated complex GO:0005515: protein binding GO:0004660: protein farnesyltransferase activity GO:0004661: protein geranylgeranyltransferase activity GO:0004662: CAAX-protein geranylgeranyltransferase activity GO:0004663: Rab geranylgeranyltransferase activity GO:0030971: receptor tyrosine kinase binding GO:0008017: microtubule binding GO:0030548: acetylcholine receptor regulator activity GO:0043014: alpha-tubulin binding |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 20406948 | Driven to death: inhibition of farnesylation increases Ras activity in osteosarcoma and promotes growth arrest and cell death. | no | no |
| title | all | all |