General Information
Gene ID | 23462 |
---|---|
Gene Symbol | HEY1 |
Gene Name | hairy/enhancer-of-split related with YRPW motif 1 |
Gene Type | protein-coding |
Cytoband | 8q21 |
Ensembl ID | ENSG00000164683 |
#miR regulators | 8 |
Omim ID | 602953 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001525: angiogenesis GO:0001570: vasculogenesis GO:0002076: osteoblast development GO:0003184: pulmonary valve morphogenesis GO:0003190: atrioventricular valve formation GO:0003198: epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003199: endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003203: endocardial cushion morphogenesis GO:0003208: cardiac ventricle morphogenesis GO:0003222: ventricular trabecula myocardium morphogenesis GO:0007219: Notch signaling pathway GO:0009948: anterior/posterior axis specification GO:0045892: negative regulation of transcription, DNA-dependent GO:0035912: dorsal aorta morphogenesis GO:0036304: umbilical cord morphogenesis GO:0045669: positive regulation of osteoblast differentiation GO:0045746: negative regulation of Notch signaling pathway GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0060317: cardiac epithelial to mesenchymal transition GO:0060347: heart trabecula formation GO:0060411: cardiac septum morphogenesis GO:0060412: ventricular septum morphogenesis GO:0060716: labyrinthine layer blood vessel development GO:0060842: arterial endothelial cell differentiation GO:0061314: Notch signaling involved in heart development GO:2000678: negative regulation of transcription regulatory region DNA binding GO:2000820: negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation GO:2001212: regulation of vasculogenesis GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0005515: protein binding GO:0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity GO:0000988: protein binding transcription factor activity GO:0003700: sequence-specific DNA binding transcription factor activity GO:0046983: protein dimerization activity GO:0008134: transcription factor binding GO:0035939: microsatellite binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
19228774 | Notch signaling contributes to the pathogenesis of human osteosarcomas. | no | no |
19455146 | Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. | no | no |
title | all | all |