Results for HEY1

General Information

Gene ID 23462
Gene Symbol HEY1
Gene Name hairy/enhancer-of-split related with YRPW motif 1
Gene Type protein-coding
Cytoband 8q21
Ensembl ID ENSG00000164683
#miR regulators 8
Omim ID 602953
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001525: angiogenesis
GO:0001570: vasculogenesis
GO:0002076: osteoblast development
GO:0003184: pulmonary valve morphogenesis
GO:0003190: atrioventricular valve formation
GO:0003198: epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003199: endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0003203: endocardial cushion morphogenesis
GO:0003208: cardiac ventricle morphogenesis
GO:0003222: ventricular trabecula myocardium morphogenesis
GO:0007219: Notch signaling pathway
GO:0009948: anterior/posterior axis specification
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0035912: dorsal aorta morphogenesis
GO:0036304: umbilical cord morphogenesis
GO:0045669: positive regulation of osteoblast differentiation
GO:0045746: negative regulation of Notch signaling pathway
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0060317: cardiac epithelial to mesenchymal transition
GO:0060347: heart trabecula formation
GO:0060411: cardiac septum morphogenesis
GO:0060412: ventricular septum morphogenesis
GO:0060716: labyrinthine layer blood vessel development
GO:0060842: arterial endothelial cell differentiation
GO:0061314: Notch signaling involved in heart development
GO:2000678: negative regulation of transcription regulatory region DNA binding
GO:2000820: negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
GO:2001212: regulation of vasculogenesis
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005515: protein binding
GO:0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0000988: protein binding transcription factor activity
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0046983: protein dimerization activity
GO:0008134: transcription factor binding
GO:0035939: microsatellite binding
KEGG pathways ---

PubMed abstracts associated with HEY1

PMID Title Tumor Value
19228774 Notch signaling contributes to the pathogenesis of human osteosarcomas. no no
19455146 Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. no no
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