Results for HEY2

General Information

Gene ID 23493
Gene Symbol HEY2
Gene Name hairy/enhancer-of-split related with YRPW motif 2
Gene Type protein-coding
Cytoband 6q21
Ensembl ID ENSG00000135547
#miR regulators 19
Omim ID 604674
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001570: vasculogenesis
GO:0003150: muscular septum morphogenesis
GO:0003151: outflow tract morphogenesis
GO:0003171: atrioventricular valve development
GO:0003184: pulmonary valve morphogenesis
GO:0003186: tricuspid valve morphogenesis
GO:0003195: tricuspid valve formation
GO:0003199: endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0003208: cardiac ventricle morphogenesis
GO:0003214: cardiac left ventricle morphogenesis
GO:0003215: cardiac right ventricle morphogenesis
GO:0003222: ventricular trabecula myocardium morphogenesis
GO:0007219: Notch signaling pathway
GO:0009948: anterior/posterior axis specification
GO:0010460: positive regulation of heart rate
GO:0010621: negative regulation of transcription by transcription factor localization
GO:0010629: negative regulation of gene expression
GO:0010667: negative regulation of cardiac muscle cell apoptotic process
GO:0014031: mesenchymal cell development
GO:0014898: cardiac muscle hypertrophy in response to stress
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0035910: ascending aorta morphogenesis
GO:0035912: dorsal aorta morphogenesis
GO:0036304: umbilical cord morphogenesis
GO:0045165: cell fate commitment
GO:0045607: regulation of auditory receptor cell differentiation
GO:0045746: negative regulation of Notch signaling pathway
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0051145: smooth muscle cell differentiation
GO:0055015: ventricular cardiac muscle cell development
GO:0060045: positive regulation of cardiac muscle cell proliferation
GO:0060317: cardiac epithelial to mesenchymal transition
GO:0060347: heart trabecula formation
GO:0060411: cardiac septum morphogenesis
GO:0060412: ventricular septum morphogenesis
GO:0060413: atrial septum morphogenesis
GO:0060633: negative regulation of transcription initiation from RNA polymerase II promoter
GO:0060716: labyrinthine layer blood vessel development
GO:0060842: arterial endothelial cell differentiation
GO:0060948: cardiac vascular smooth muscle cell development
GO:0060977: coronary vasculature morphogenesis
GO:0061156: pulmonary artery morphogenesis
GO:0061314: Notch signaling involved in heart development
GO:0065004: protein-DNA complex assembly
GO:0090102: cochlea development
GO:0097084: vascular smooth muscle cell development
GO:2000678: negative regulation of transcription regulatory region DNA binding
GO:2000723: negative regulation of cardiac vascular smooth muscle cell differentiation
GO:2000820: negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
GO:2001212: regulation of vasculogenesis
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0016580: Sin3 complex
GO:0017053: transcriptional repressor complex
GO:0005515: protein binding
GO:0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0000988: protein binding transcription factor activity
GO:0001102: RNA polymerase II activating transcription factor binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0046983: protein dimerization activity
GO:0008134: transcription factor binding
GO:0035939: microsatellite binding
GO:0042826: histone deacetylase binding
GO:0043565: sequence-specific DNA binding
KEGG pathways ---

PubMed abstracts associated with HEY2

PMID Title Tumor Value
19455146 Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. no no
title all all