General Information
Gene ID | 23493 |
---|---|
Gene Symbol | HEY2 |
Gene Name | hairy/enhancer-of-split related with YRPW motif 2 |
Gene Type | protein-coding |
Cytoband | 6q21 |
Ensembl ID | ENSG00000135547 |
#miR regulators | 19 |
Omim ID | 604674 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001570: vasculogenesis GO:0003150: muscular septum morphogenesis GO:0003151: outflow tract morphogenesis GO:0003171: atrioventricular valve development GO:0003184: pulmonary valve morphogenesis GO:0003186: tricuspid valve morphogenesis GO:0003195: tricuspid valve formation GO:0003199: endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003208: cardiac ventricle morphogenesis GO:0003214: cardiac left ventricle morphogenesis GO:0003215: cardiac right ventricle morphogenesis GO:0003222: ventricular trabecula myocardium morphogenesis GO:0007219: Notch signaling pathway GO:0009948: anterior/posterior axis specification GO:0010460: positive regulation of heart rate GO:0010621: negative regulation of transcription by transcription factor localization GO:0010629: negative regulation of gene expression GO:0010667: negative regulation of cardiac muscle cell apoptotic process GO:0014031: mesenchymal cell development GO:0014898: cardiac muscle hypertrophy in response to stress GO:0045892: negative regulation of transcription, DNA-dependent GO:0035910: ascending aorta morphogenesis GO:0035912: dorsal aorta morphogenesis GO:0036304: umbilical cord morphogenesis GO:0045165: cell fate commitment GO:0045607: regulation of auditory receptor cell differentiation GO:0045746: negative regulation of Notch signaling pathway GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0051145: smooth muscle cell differentiation GO:0055015: ventricular cardiac muscle cell development GO:0060045: positive regulation of cardiac muscle cell proliferation GO:0060317: cardiac epithelial to mesenchymal transition GO:0060347: heart trabecula formation GO:0060411: cardiac septum morphogenesis GO:0060412: ventricular septum morphogenesis GO:0060413: atrial septum morphogenesis GO:0060633: negative regulation of transcription initiation from RNA polymerase II promoter GO:0060716: labyrinthine layer blood vessel development GO:0060842: arterial endothelial cell differentiation GO:0060948: cardiac vascular smooth muscle cell development GO:0060977: coronary vasculature morphogenesis GO:0061156: pulmonary artery morphogenesis GO:0061314: Notch signaling involved in heart development GO:0065004: protein-DNA complex assembly GO:0090102: cochlea development GO:0097084: vascular smooth muscle cell development GO:2000678: negative regulation of transcription regulatory region DNA binding GO:2000723: negative regulation of cardiac vascular smooth muscle cell differentiation GO:2000820: negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation GO:2001212: regulation of vasculogenesis GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0016580: Sin3 complex GO:0017053: transcriptional repressor complex GO:0005515: protein binding GO:0000983: RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity GO:0000988: protein binding transcription factor activity GO:0001102: RNA polymerase II activating transcription factor binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0046983: protein dimerization activity GO:0008134: transcription factor binding GO:0035939: microsatellite binding GO:0042826: histone deacetylase binding GO:0043565: sequence-specific DNA binding |
KEGG pathways | --- |
PMID | Title | Tumor | Value |
---|---|---|---|
19455146 | Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. | no | no |
title | all | all |