General Information
| Gene ID | 23532 |
|---|---|
| Gene Symbol | PRAME |
| Gene Name | preferentially expressed antigen in melanoma |
| Gene Type | protein-coding |
| Cytoband | 22q11.22 |
| Ensembl ID | ENSG00000185686 |
| #miR regulators | 1 |
| Omim ID | 606021 |
| Gene ontology |
GO:0006915: apoptotic process GO:0006351: transcription, DNA-dependent GO:0043066: negative regulation of apoptotic process GO:0008284: positive regulation of cell proliferation GO:0045892: negative regulation of transcription, DNA-dependent GO:0030154: cell differentiation GO:0040008: regulation of growth GO:0045596: negative regulation of cell differentiation GO:0048387: negative regulation of retinoic acid receptor signaling pathway GO:0005886: plasma membrane GO:0005634: nucleus GO:0005515: protein binding GO:0042974: retinoic acid receptor binding |
| KEGG pathways | --- |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 21691740 | Insights on PRAME and osteosarcoma by means of gene expression profiling. | yes | no |
| 22009167 | Cancer-testis antigens expressed in osteosarcoma identified by gene microarray correlate with a poor patient prognosis. | yes | yes |
| 22390931 | Expression and prognostic relevance of PRAME in primary osteosarcoma. | yes | yes |
| title | all | all |