Results for GAS6

General Information

Gene ID 2621
Gene Symbol GAS6
Gene Name growth arrest-specific 6
Gene Type protein-coding
Cytoband 13q34
Ensembl ID ENSG00000183087
#miR regulators ---
Omim ID 600441
Gene ontology GO:0001764: neuron migration
GO:0001934: positive regulation of protein phosphorylation
GO:0001961: positive regulation of cytokine-mediated signaling pathway
GO:0002576: platelet degranulation
GO:0003104: positive regulation of glomerular filtration
GO:0007596: blood coagulation
GO:0007155: cell adhesion
GO:0007165: signal transduction
GO:0006468: protein phosphorylation
GO:0006508: proteolysis
GO:0006909: phagocytosis
GO:0007050: cell cycle arrest
GO:0007167: enzyme linked receptor protein signaling pathway
GO:0019079: viral genome replication
GO:0043066: negative regulation of apoptotic process
GO:0008283: cell proliferation
GO:0009267: cellular response to starvation
GO:0010628: positive regulation of gene expression
GO:0010804: negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010934: macrophage cytokine production
GO:0016477: cell migration
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0017187: peptidyl-glutamic acid carboxylation
GO:0018105: peptidyl-serine phosphorylation
GO:0019064: viral entry into host cell via membrane fusion with the plasma membrane
GO:0046718: viral entry into host cell
GO:0030168: platelet activation
GO:0031100: organ regeneration
GO:0031589: cell-substrate adhesion
GO:0032008: positive regulation of TOR signaling cascade
GO:0032148: activation of protein kinase B activity
GO:0032689: negative regulation of interferon-gamma production
GO:0032715: negative regulation of interleukin-6 production
GO:0032720: negative regulation of tumor necrosis factor production
GO:0032825: positive regulation of natural killer cell differentiation
GO:0033138: positive regulation of peptidyl-serine phosphorylation
GO:0033159: negative regulation of protein import into nucleus, translocation
GO:0035457: cellular response to interferon-alpha
GO:0035690: cellular response to drug
GO:0035754: B cell chemotaxis
GO:0040008: regulation of growth
GO:0043154: negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043277: apoptotic cell clearance
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043491: protein kinase B signaling cascade
GO:0043687: post-translational protein modification
GO:0044267: cellular protein metabolic process
GO:0045860: positive regulation of protein kinase activity
GO:0046813: virion attachment, binding of host cell surface receptor
GO:0046827: positive regulation of protein export from nucleus
GO:0048146: positive regulation of fibroblast proliferation
GO:0050711: negative regulation of interleukin-1 secretion
GO:0050766: positive regulation of phagocytosis
GO:0050900: leukocyte migration
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0061098: positive regulation of protein tyrosine kinase activity
GO:0070168: negative regulation of biomineral tissue development
GO:0070374: positive regulation of ERK1 and ERK2 cascade
GO:0070527: platelet aggregation
GO:0070588: calcium ion transmembrane transport
GO:0071307: cellular response to vitamin K
GO:0071333: cellular response to glucose stimulus
GO:0071363: cellular response to growth factor stimulus
GO:0072661: protein targeting to plasma membrane
GO:0085029: extracellular matrix assembly
GO:0097028: dendritic cell differentiation
GO:0097241: hematopoietic stem cell migration to bone marrow
GO:1900142: negative regulation of oligodendrocyte apoptotic process
GO:1900165: negative regulation of interleukin-6 secretion
GO:2000270: negative regulation of fibroblast apoptotic process
GO:2000352: negative regulation of endothelial cell apoptotic process
GO:2000510: positive regulation of dendritic cell chemotaxis
GO:2000533: negative regulation of renal albumin absorption
GO:2000669: negative regulation of dendritic cell apoptotic process
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005737: cytoplasm
GO:0005788: endoplasmic reticulum lumen
GO:0005796: Golgi lumen
GO:0031093: platelet alpha granule lumen
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0001786: phosphatidylserine binding
GO:0005102: receptor binding
GO:0005245: voltage-gated calcium channel activity
GO:0030971: receptor tyrosine kinase binding
GO:0048018: receptor agonist activity
GO:0030296: protein tyrosine kinase activator activity
GO:0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0060090: binding, bridging
KEGG pathways ---

PubMed abstracts associated with GAS6

PMID Title Tumor Value
23684620 Gas6/Axl mediates tumor cell apoptosis, migration and invasion and predicts the clinical outcome of osteosarcoma patients. yes yes
title all all