Results for GDF2

General Information

Gene ID 2658
Gene Symbol GDF2
Gene Name growth differentiation factor 2
Gene Type protein-coding
Cytoband 10q11.22
Ensembl ID ENSG00000128802 ENSG00000263761
#miR regulators 3
Omim ID 605120
Gene ontology GO:0001503: ossification
GO:0001569: patterning of blood vessels
GO:0001570: vasculogenesis
GO:0001649: osteoblast differentiation
GO:0001937: negative regulation of endothelial cell proliferation
GO:0001938: positive regulation of endothelial cell proliferation
GO:0006879: cellular iron ion homeostasis
GO:0040007: growth
GO:0008156: negative regulation of DNA replication
GO:0010596: negative regulation of endothelial cell migration
GO:0010862: positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016525: negative regulation of angiogenesis
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0030308: negative regulation of cell growth
GO:0030509: BMP signaling pathway
GO:0030513: positive regulation of BMP signaling pathway
GO:0032757: positive regulation of interleukin-8 production
GO:0032924: activin receptor signaling pathway
GO:0043537: negative regulation of blood vessel endothelial cell migration
GO:0045603: positive regulation of endothelial cell differentiation
GO:0045669: positive regulation of osteoblast differentiation
GO:0045766: positive regulation of angiogenesis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048514: blood vessel morphogenesis
GO:0051216: cartilage development
GO:0060389: pathway-restricted SMAD protein phosphorylation
GO:2000279: negative regulation of DNA biosynthetic process
GO:0005615: extracellular space
GO:0005515: protein binding
GO:0005125: cytokine activity
GO:0008083: growth factor activity
KEGG pathways ---

PubMed abstracts associated with GDF2

PMID Title Tumor Value
22948234 Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway. no no
23262982 Preventing MEK1 activation influences the responses of human osteosarcoma cells to bone morphogenetic proteins 2 and 9. no no
title all all