General Information
Gene ID | 2688 |
---|---|
Gene Symbol | GH1 |
Gene Name | growth hormone 1 |
Gene Type | protein-coding |
Cytoband | 17q24.2 |
Ensembl ID | ENSG00000259384 ENSG00000136488 |
#miR regulators | 1 |
Omim ID | 139250 173100 262400 262650 612781 |
Gene ontology |
GO:0007259: JAK-STAT cascade GO:0010535: positive regulation of activation of JAK2 kinase activity GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade GO:0015758: glucose transport GO:0032355: response to estradiol stimulus GO:0040018: positive regulation of multicellular organism growth GO:0042517: positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042523: positive regulation of tyrosine phosphorylation of Stat5 protein GO:0043406: positive regulation of MAP kinase activity GO:0043568: positive regulation of insulin-like growth factor receptor signaling pathway GO:0046427: positive regulation of JAK-STAT cascade GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation GO:0060396: growth hormone receptor signaling pathway GO:0060397: JAK-STAT cascade involved in growth hormone signaling pathway GO:0070977: bone maturation GO:0005576: extracellular region GO:0005615: extracellular space GO:0005515: protein binding GO:0005131: growth hormone receptor binding GO:0005148: prolactin receptor binding GO:0005179: hormone activity GO:0046872: metal ion binding GO:0008083: growth factor activity |
KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4080: Neuroactive ligand-receptor interaction 4630: Jak-STAT signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
12218590 | Treatment of metastatic osteosarcoma with the somatostatin analog OncoLar: significant reduction of insulin-like growth factor-1 serum levels. | yes | no |
21619704 | A comprehensive candidate gene approach identifies genetic variation associated with osteosarcoma. | yes | yes |
title | all | all |