Results for GLI1

General Information

Gene ID 2735
Gene Symbol GLI1
Gene Name GLI family zinc finger 1
Gene Type protein-coding
Cytoband 12q13.2-q13.3
Ensembl ID ENSG00000111087
#miR regulators ---
Omim ID 165220
Gene ontology GO:0001649: osteoblast differentiation
GO:0007224: smoothened signaling pathway
GO:0007283: spermatogenesis
GO:0007418: ventral midline development
GO:0008284: positive regulation of cell proliferation
GO:0008589: regulation of smoothened signaling pathway
GO:0009913: epidermal cell differentiation
GO:0009953: dorsal/ventral pattern formation
GO:0009954: proximal/distal pattern formation
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0021696: cerebellar cortex morphogenesis
GO:0021938: smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
GO:0021983: pituitary gland development
GO:0030324: lung development
GO:0045740: positive regulation of DNA replication
GO:0045880: positive regulation of smoothened signaling pathway
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048546: digestive tract morphogenesis
GO:0060032: notochord regression
GO:0090090: negative regulation of canonical Wnt receptor signaling pathway
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0072372: primary cilium
GO:0005515: protein binding
GO:0003677: DNA binding
GO:0003682: chromatin binding
GO:0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0046872: metal ion binding
GO:0008017: microtubule binding
GO:0044212: transcription regulatory region DNA binding
KEGG pathways 4340: Hedgehog signaling pathway
5200: Pathways in cancer
5217: Basal cell carcinoma

PubMed abstracts associated with GLI1

PMID Title Tumor Value
8117620 Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2. yes no
20067614 Smoothened as a new therapeutic target for human osteosarcoma. yes no
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