General Information
| Gene ID | 2752 |
|---|---|
| Gene Symbol | GLUL |
| Gene Name | glutamate-ammonia ligase |
| Gene Type | protein-coding |
| Cytoband | 1q31 |
| Ensembl ID | ENSG00000135821 |
| #miR regulators | 11 |
| Omim ID | 138290 610015 |
| Gene ontology |
GO:0001504: neurotransmitter uptake GO:0006538: glutamate catabolic process GO:0006542: glutamine biosynthetic process GO:0007268: synaptic transmission GO:0008283: cell proliferation GO:0008652: cellular amino acid biosynthetic process GO:0009749: response to glucose stimulus GO:0032024: positive regulation of insulin secretion GO:0034641: cellular nitrogen compound metabolic process GO:0051260: protein homooligomerization GO:0044281: small molecule metabolic process GO:0050679: positive regulation of epithelial cell proliferation GO:0051968: positive regulation of synaptic transmission, glutamatergic GO:0005739: mitochondrion GO:0005829: cytosol GO:0005791: rough endoplasmic reticulum GO:0043204: perikaryon GO:0043234: protein complex GO:0043679: axon terminus GO:0000287: magnesium ion binding GO:0004351: glutamate decarboxylase activity GO:0004356: glutamate-ammonia ligase activity GO:0005524: ATP binding GO:0016595: glutamate binding GO:0042802: identical protein binding GO:0030145: manganese ion binding GO:0045503: dynein light chain binding |
| KEGG pathways |
250: Alanine, aspartate and glutamate metabolism 330: Arginine and proline metabolism 910: Nitrogen metabolism 1100: Metabolic pathways |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 17256128 | The inhibition of glutamine synthetase sensitizes human sarcoma cells to L-asparaginase. | no | no |
| title | all | all |