Results for DLL1

General Information

Gene ID 28514
Gene Symbol DLL1
Gene Name delta-like 1 (Drosophila)
Gene Type protein-coding
Cytoband 6q27
Ensembl ID ENSG00000198719
#miR regulators 14
Omim ID 606582
Gene ontology GO:0001709: cell fate determination
GO:0001757: somite specification
GO:0001947: heart looping
GO:0007219: Notch signaling pathway
GO:0007220: Notch receptor processing
GO:0007267: cell-cell signaling
GO:0007368: determination of left/right symmetry
GO:0007386: compartment pattern specification
GO:0030097: hemopoiesis
GO:0030154: cell differentiation
GO:0030155: regulation of cell adhesion
GO:0045608: negative regulation of auditory receptor cell differentiation
GO:0045638: negative regulation of myeloid cell differentiation
GO:0045747: positive regulation of Notch signaling pathway
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048839: inner ear development
GO:0070986: left/right axis specification
GO:0072014: proximal tubule development
GO:0072070: loop of Henle development
GO:0097150: neuronal stem cell maintenance
GO:0005886: plasma membrane
GO:0005576: extracellular region
GO:0005887: integral to plasma membrane
GO:0031410: cytoplasmic vesicle
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0005112: Notch binding
KEGG pathways 4330: Notch signaling pathway

PubMed abstracts associated with DLL1

PMID Title Tumor Value
18483362 Critical role of notch signaling in osteosarcoma invasion and metastasis. yes yes
19455146 Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. no no
20213410 How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize. no yes
title all all