Results for H2AFX

General Information

Gene ID 3014
Gene Symbol H2AFX
Gene Name H2A histone family, member X
Gene Type protein-coding
Cytoband 11q23.3
Ensembl ID ENSG00000188486
#miR regulators 3
Omim ID 601772
Gene ontology GO:0000077: DNA damage checkpoint
GO:0000724: double-strand break repair via homologous recombination
GO:0006334: nucleosome assembly
GO:0006281: DNA repair
GO:0006302: double-strand break repair
GO:0006974: response to DNA damage stimulus
GO:0007126: meiosis
GO:0007283: spermatogenesis
GO:0010212: response to ionizing radiation
GO:0045739: positive regulation of DNA repair
GO:0000794: condensed nuclear chromosome
GO:0000781: chromosome, telomeric region
GO:0000786: nucleosome
GO:0000790: nuclear chromatin
GO:0001673: male germ cell nucleus
GO:0001741: XY body
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005657: replication fork
GO:0005515: protein binding
GO:0003677: DNA binding
GO:0003684: damaged DNA binding
GO:0042393: histone binding
GO:0019899: enzyme binding
GO:0046982: protein heterodimerization activity
KEGG pathways 5322: Systemic lupus erythematosus

PubMed abstracts associated with H2AFX

PMID Title Tumor Value
17218778 Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells. no no
17611684 Zoledronate-induced S phase arrest and apoptosis accompanied by DNA damage and activation of the ATM/Chk1/cdc25 pathway in human osteosarcoma cells. no no
19159633 Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage. no no
19559722 Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1. no no
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