Results for HDAC1

General Information

Gene ID 3065
Gene Symbol HDAC1
Gene Name histone deacetylase 1
Gene Type protein-coding
Cytoband 1p34
Ensembl ID ENSG00000116478
#miR regulators 6
Omim ID 601241
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0000278: mitotic cell cycle
GO:0007596: blood coagulation
GO:0006338: chromatin remodeling
GO:0006351: transcription, DNA-dependent
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006476: protein deacetylation
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0007219: Notch signaling pathway
GO:0043066: negative regulation of apoptotic process
GO:0008284: positive regulation of cell proliferation
GO:0009913: epidermal cell differentiation
GO:0010467: gene expression
GO:0010870: positive regulation of receptor biosynthetic process
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0016568: chromatin modification
GO:0016575: histone deacetylation
GO:0019048: modulation by virus of host morphology or physiology
GO:0042475: odontogenesis of dentin-containing tooth
GO:0042733: embryonic digit morphogenesis
GO:0043922: negative regulation by host of viral transcription
GO:0045786: negative regulation of cell cycle
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0060766: negative regulation of androgen receptor signaling pathway
GO:0060789: hair follicle placode formation
GO:0061029: eyelid development in camera-type eye
GO:0061198: fungiform papilla formation
GO:0070932: histone H3 deacetylation
GO:0070933: histone H4 deacetylation
GO:0000118: histone deacetylase complex
GO:0000790: nuclear chromatin
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0016580: Sin3 complex
GO:0016581: NuRD complex
GO:0005515: protein binding
GO:0001047: core promoter binding
GO:0001103: RNA polymerase II repressing transcription factor binding
GO:0001106: RNA polymerase II transcription corepressor activity
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0004407: histone deacetylase activity
GO:0008134: transcription factor binding
GO:0019899: enzyme binding
GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558: protein deacetylase activity
GO:0033613: activating transcription factor binding
GO:0042826: histone deacetylase binding
GO:0046969: NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970: NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0097372: NAD-dependent histone deacetylase activity (H3-K18 specific)
KEGG pathways 4110: Cell cycle
4330: Notch signaling pathway
5016: Huntington's disease
5200: Pathways in cancer
5220: Chronic myeloid leukemia

PubMed abstracts associated with HDAC1

PMID Title Tumor Value
12789260 Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes. no no
17234448 Modulation of apoptotic signalling by 9-hydroxystearic acid in osteosarcoma cells. no no
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