General Information
Gene ID | 3065 |
---|---|
Gene Symbol | HDAC1 |
Gene Name | histone deacetylase 1 |
Gene Type | protein-coding |
Cytoband | 1p34 |
Ensembl ID | ENSG00000116478 |
#miR regulators | 6 |
Omim ID | 601241 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0000278: mitotic cell cycle GO:0007596: blood coagulation GO:0006338: chromatin remodeling GO:0006351: transcription, DNA-dependent GO:0006367: transcription initiation from RNA polymerase II promoter GO:0006476: protein deacetylation GO:0007179: transforming growth factor beta receptor signaling pathway GO:0007219: Notch signaling pathway GO:0043066: negative regulation of apoptotic process GO:0008284: positive regulation of cell proliferation GO:0009913: epidermal cell differentiation GO:0010467: gene expression GO:0010870: positive regulation of receptor biosynthetic process GO:0045893: positive regulation of transcription, DNA-dependent GO:0045892: negative regulation of transcription, DNA-dependent GO:0016568: chromatin modification GO:0016575: histone deacetylation GO:0019048: modulation by virus of host morphology or physiology GO:0042475: odontogenesis of dentin-containing tooth GO:0042733: embryonic digit morphogenesis GO:0043922: negative regulation by host of viral transcription GO:0045786: negative regulation of cell cycle GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048011: neurotrophin TRK receptor signaling pathway GO:0060766: negative regulation of androgen receptor signaling pathway GO:0060789: hair follicle placode formation GO:0061029: eyelid development in camera-type eye GO:0061198: fungiform papilla formation GO:0070932: histone H3 deacetylation GO:0070933: histone H4 deacetylation GO:0000118: histone deacetylase complex GO:0000790: nuclear chromatin GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005654: nucleoplasm GO:0016580: Sin3 complex GO:0016581: NuRD complex GO:0005515: protein binding GO:0001047: core promoter binding GO:0001103: RNA polymerase II repressing transcription factor binding GO:0001106: RNA polymerase II transcription corepressor activity GO:0003700: sequence-specific DNA binding transcription factor activity GO:0004407: histone deacetylase activity GO:0008134: transcription factor binding GO:0019899: enzyme binding GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0033558: protein deacetylase activity GO:0033613: activating transcription factor binding GO:0042826: histone deacetylase binding GO:0046969: NAD-dependent histone deacetylase activity (H3-K9 specific) GO:0046970: NAD-dependent histone deacetylase activity (H4-K16 specific) GO:0097372: NAD-dependent histone deacetylase activity (H3-K18 specific) |
KEGG pathways |
4110: Cell cycle 4330: Notch signaling pathway 5016: Huntington's disease 5200: Pathways in cancer 5220: Chronic myeloid leukemia |
PMID | Title | Tumor | Value |
---|---|---|---|
12789260 | Triggering of p73-dependent apoptosis in osteosarcoma is under the control of E2Fs-pRb2/p130 complexes. | no | no |
17234448 | Modulation of apoptotic signalling by 9-hydroxystearic acid in osteosarcoma cells. | no | no |
title | all | all |