Results for HDAC2

General Information

Gene ID 3066
Gene Symbol HDAC2
Gene Name histone deacetylase 2
Gene Type protein-coding
Cytoband 6q21
Ensembl ID ENSG00000196591
#miR regulators 14
Omim ID 605164
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0007596: blood coagulation
GO:0006338: chromatin remodeling
GO:0006344: maintenance of chromatin silencing
GO:0006351: transcription, DNA-dependent
GO:0043066: negative regulation of apoptotic process
GO:0008284: positive regulation of cell proliferation
GO:0009913: epidermal cell differentiation
GO:0010870: positive regulation of receptor biosynthetic process
GO:0010977: negative regulation of neuron projection development
GO:0016358: dendrite development
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0016575: histone deacetylation
GO:0021766: hippocampus development
GO:0032967: positive regulation of collagen biosynthetic process
GO:0042475: odontogenesis of dentin-containing tooth
GO:0042733: embryonic digit morphogenesis
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045347: negative regulation of MHC class II biosynthetic process
GO:0045786: negative regulation of cell cycle
GO:0045862: positive regulation of proteolysis
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0048714: positive regulation of oligodendrocyte differentiation
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051896: regulation of protein kinase B signaling cascade
GO:0055013: cardiac muscle cell development
GO:0060044: negative regulation of cardiac muscle cell proliferation
GO:0060297: regulation of sarcomere organization
GO:0060789: hair follicle placode formation
GO:0061029: eyelid development in camera-type eye
GO:0061198: fungiform papilla formation
GO:0090090: negative regulation of canonical Wnt receptor signaling pathway
GO:0090311: regulation of protein deacetylation
GO:0000792: heterochromatin
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005657: replication fork
GO:0005667: transcription factor complex
GO:0016580: Sin3 complex
GO:0016581: NuRD complex
GO:0035098: ESC/E(Z) complex
GO:0005515: protein binding
GO:0001103: RNA polymerase II repressing transcription factor binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0004407: histone deacetylase activity
GO:0008134: transcription factor binding
GO:0019899: enzyme binding
GO:0031490: chromatin DNA binding
GO:0032041: NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0033558: protein deacetylase activity
GO:0043565: sequence-specific DNA binding
GO:0046969: NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970: NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0097372: NAD-dependent histone deacetylase activity (H3-K18 specific)
KEGG pathways 4110: Cell cycle
4330: Notch signaling pathway
5016: Huntington's disease
5200: Pathways in cancer
5220: Chronic myeloid leukemia

PubMed abstracts associated with HDAC2

PMID Title Tumor Value
17980151 Cell-specific epigenetic regulation of ChM-I gene expression: crosstalk between DNA methylation and histone acetylation. no no
title all all