Results for HMGB1

General Information

Gene ID 3146
Gene Symbol HMGB1
Gene Name high mobility group box 1
Gene Type protein-coding
Cytoband 13q12
Ensembl ID ENSG00000189403
#miR regulators 9
Omim ID 163905
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001773: myeloid dendritic cell activation
GO:0002407: dendritic cell chemotaxis
GO:0002437: inflammatory response to antigenic stimulus
GO:0006915: apoptotic process
GO:0006265: DNA topological change
GO:0006288: base-excision repair, DNA ligation
GO:0006309: apoptotic DNA fragmentation
GO:0006310: DNA recombination
GO:0006357: regulation of transcription from RNA polymerase II promoter
GO:0006921: cellular component disassembly involved in execution phase of apoptosis
GO:0017055: negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:0031175: neuron projection development
GO:0033151: V(D)J recombination
GO:0043065: positive regulation of apoptotic process
GO:0043280: positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043388: positive regulation of DNA binding
GO:0045087: innate immune response
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0050918: positive chemotaxis
GO:0051103: DNA ligation involved in DNA repair
GO:2000426: negative regulation of apoptotic cell clearance
GO:0000793: condensed chromosome
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0009986: cell surface
GO:0017053: transcriptional repressor complex
GO:0005515: protein binding
GO:0003684: damaged DNA binding
GO:0003690: double-stranded DNA binding
GO:0003697: single-stranded DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0005125: cytokine activity
GO:0008134: transcription factor binding
GO:0008301: DNA binding, bending
GO:0042056: chemoattractant activity
GO:0050786: RAGE receptor binding
GO:0070491: repressing transcription factor binding
KEGG pathways 3410: Base excision repair

PubMed abstracts associated with HMGB1

PMID Title Tumor Value
22102692 HMGB1 promotes drug resistance in osteosarcoma. no no
22301993 Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma. no no
title all all