Results for BIRC2

General Information

Gene ID 329
Gene Symbol BIRC2
Gene Name baculoviral IAP repeat containing 2
Gene Type protein-coding
Cytoband 11q22
Ensembl ID ENSG00000110330
#miR regulators 6
Omim ID 601712
Gene ontology GO:0000209: protein polyubiquitination
GO:0001890: placenta development
GO:0002224: toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0051726: regulation of cell cycle
GO:0006915: apoptotic process
GO:0006351: transcription, DNA-dependent
GO:0006355: regulation of transcription, DNA-dependent
GO:0006921: cellular component disassembly involved in execution phase of apoptosis
GO:0007166: cell surface receptor signaling pathway
GO:0043066: negative regulation of apoptotic process
GO:0034121: regulation of toll-like receptor signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0038061: NIK/NF-kappaB cascade
GO:0039535: regulation of RIG-I signaling pathway
GO:0042127: regulation of cell proliferation
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043161: proteasomal ubiquitin-dependent protein catabolic process
GO:0045087: innate immune response
GO:0045088: regulation of innate immune response
GO:0045595: regulation of cell differentiation
GO:0050727: regulation of inflammatory response
GO:0070266: necroptosis
GO:0070424: regulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:2000116: regulation of cysteine-type endopeptidase activity
GO:0005829: cytosol
GO:0005634: nucleus
GO:0009898: internal side of plasma membrane
GO:0035631: CD40 receptor complex
GO:0005515: protein binding
GO:0003713: transcription coactivator activity
GO:0004842: ubiquitin-protein ligase activity
GO:0008270: zinc ion binding
GO:0047485: protein N-terminus binding
KEGG pathways 4120: Ubiquitin mediated proteolysis
4210: Apoptosis
4510: Focal adhesion
4621: NOD-like receptor signaling pathway
5145: Toxoplasmosis
5200: Pathways in cancer
5222: Small cell lung cancer

PubMed abstracts associated with BIRC2

PMID Title Tumor Value
11093825 Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression. no no
23164673 The glycogen synthase kinase-3β/nuclear factor-kappa B pathway is involved in cinobufagin-induced apoptosis in cultured osteosarcoma cells. no no
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