General Information
| Gene ID | 329 |
|---|---|
| Gene Symbol | BIRC2 |
| Gene Name | baculoviral IAP repeat containing 2 |
| Gene Type | protein-coding |
| Cytoband | 11q22 |
| Ensembl ID | ENSG00000110330 |
| #miR regulators | 6 |
| Omim ID | 601712 |
| Gene ontology |
GO:0000209: protein polyubiquitination GO:0001890: placenta development GO:0002224: toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0051726: regulation of cell cycle GO:0006915: apoptotic process GO:0006351: transcription, DNA-dependent GO:0006355: regulation of transcription, DNA-dependent GO:0006921: cellular component disassembly involved in execution phase of apoptosis GO:0007166: cell surface receptor signaling pathway GO:0043066: negative regulation of apoptotic process GO:0034121: regulation of toll-like receptor signaling pathway GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0038061: NIK/NF-kappaB cascade GO:0039535: regulation of RIG-I signaling pathway GO:0042127: regulation of cell proliferation GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043161: proteasomal ubiquitin-dependent protein catabolic process GO:0045087: innate immune response GO:0045088: regulation of innate immune response GO:0045595: regulation of cell differentiation GO:0050727: regulation of inflammatory response GO:0070266: necroptosis GO:0070424: regulation of nucleotide-binding oligomerization domain containing signaling pathway GO:2000116: regulation of cysteine-type endopeptidase activity GO:0005829: cytosol GO:0005634: nucleus GO:0009898: internal side of plasma membrane GO:0035631: CD40 receptor complex GO:0005515: protein binding GO:0003713: transcription coactivator activity GO:0004842: ubiquitin-protein ligase activity GO:0008270: zinc ion binding GO:0047485: protein N-terminus binding |
| KEGG pathways |
4120: Ubiquitin mediated proteolysis 4210: Apoptosis 4510: Focal adhesion 4621: NOD-like receptor signaling pathway 5145: Toxoplasmosis 5200: Pathways in cancer 5222: Small cell lung cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 11093825 | Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression. | no | no |
| 23164673 | The glycogen synthase kinase-3β/nuclear factor-kappa B pathway is involved in cinobufagin-induced apoptosis in cultured osteosarcoma cells. | no | no |
| title | all | all |