General Information
| Gene ID | 330 |
|---|---|
| Gene Symbol | BIRC3 |
| Gene Name | baculoviral IAP repeat containing 3 |
| Gene Type | protein-coding |
| Cytoband | 11q22 |
| Ensembl ID | ENSG00000023445 |
| #miR regulators | 4 |
| Omim ID | 601721 |
| Gene ontology |
GO:0002224: toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0006915: apoptotic process GO:0007166: cell surface receptor signaling pathway GO:0043066: negative regulation of apoptotic process GO:2000378: negative regulation of reactive oxygen species metabolic process GO:0034121: regulation of toll-like receptor signaling pathway GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0038061: NIK/NF-kappaB cascade GO:0039535: regulation of RIG-I signaling pathway GO:0042326: negative regulation of phosphorylation GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0045087: innate immune response GO:0045088: regulation of innate immune response GO:0050727: regulation of inflammatory response GO:0060546: negative regulation of necroptosis GO:0070266: necroptosis GO:0070424: regulation of nucleotide-binding oligomerization domain containing signaling pathway GO:2000116: regulation of cysteine-type endopeptidase activity GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005515: protein binding GO:0004842: ubiquitin-protein ligase activity GO:0008270: zinc ion binding |
| KEGG pathways |
4120: Ubiquitin mediated proteolysis 4210: Apoptosis 4510: Focal adhesion 4621: NOD-like receptor signaling pathway 5145: Toxoplasmosis 5200: Pathways in cancer 5222: Small cell lung cancer |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 11093825 | Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression. | no | no |
| 21527497 | Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance. | no | no |
| title | all | all |