Results for BIRC3

General Information

Gene ID 330
Gene Symbol BIRC3
Gene Name baculoviral IAP repeat containing 3
Gene Type protein-coding
Cytoband 11q22
Ensembl ID ENSG00000023445
#miR regulators 4
Omim ID 601721
Gene ontology GO:0002224: toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0006915: apoptotic process
GO:0007166: cell surface receptor signaling pathway
GO:0043066: negative regulation of apoptotic process
GO:2000378: negative regulation of reactive oxygen species metabolic process
GO:0034121: regulation of toll-like receptor signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0038061: NIK/NF-kappaB cascade
GO:0039535: regulation of RIG-I signaling pathway
GO:0042326: negative regulation of phosphorylation
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045087: innate immune response
GO:0045088: regulation of innate immune response
GO:0050727: regulation of inflammatory response
GO:0060546: negative regulation of necroptosis
GO:0070266: necroptosis
GO:0070424: regulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:2000116: regulation of cysteine-type endopeptidase activity
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005515: protein binding
GO:0004842: ubiquitin-protein ligase activity
GO:0008270: zinc ion binding
KEGG pathways 4120: Ubiquitin mediated proteolysis
4210: Apoptosis
4510: Focal adhesion
4621: NOD-like receptor signaling pathway
5145: Toxoplasmosis
5200: Pathways in cancer
5222: Small cell lung cancer

PubMed abstracts associated with BIRC3

PMID Title Tumor Value
11093825 Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression. no no
21527497 Glucocorticoid receptor alpha isoform-selective regulation of antiapoptotic genes in osteosarcoma cells: a new mechanism for glucocorticoid resistance. no no
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