Results for HSPA5

General Information

Gene ID 3309
Gene Symbol HSPA5
Gene Name heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
Gene Type protein-coding
Cytoband 9q33.3
Ensembl ID ENSG00000044574
#miR regulators 7
Omim ID 138120
Gene ontology GO:0002576: platelet degranulation
GO:0007596: blood coagulation
GO:0006200: ATP catabolic process
GO:0006983: ER overload response
GO:0006987: activation of signaling protein activity involved in unfolded protein response
GO:0043066: negative regulation of apoptotic process
GO:0021589: cerebellum structural organization
GO:0021680: cerebellar Purkinje cell layer development
GO:0030168: platelet activation
GO:0030433: ER-associated protein catabolic process
GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030968: endoplasmic reticulum unfolded protein response
GO:0031398: positive regulation of protein ubiquitination
GO:0042149: cellular response to glucose starvation
GO:0044267: cellular protein metabolic process
GO:0060904: regulation of protein folding in endoplasmic reticulum
GO:0071353: cellular response to interleukin-4
GO:0005783: endoplasmic reticulum
GO:0005634: nucleus
GO:0005788: endoplasmic reticulum lumen
GO:0005789: endoplasmic reticulum membrane
GO:0005793: endoplasmic reticulum-Golgi intermediate compartment
GO:0008180: COP9 signalosome
GO:0009986: cell surface
GO:0030176: integral to endoplasmic reticulum membrane
GO:0030496: midbody
GO:0034663: endoplasmic reticulum chaperone complex
GO:0042470: melanosome
GO:0051082: unfolded protein binding
GO:0005515: protein binding
GO:0005509: calcium ion binding
GO:0051087: chaperone binding
GO:0030674: protein binding, bridging
GO:0005524: ATP binding
GO:0016887: ATPase activity
GO:0051787: misfolded protein binding
GO:0019904: protein domain specific binding
GO:0031625: ubiquitin protein ligase binding
GO:0043022: ribosome binding
KEGG pathways 3060: Protein export
4141: Protein processing in endoplasmic reticulum
4612: Antigen processing and presentation
5020: Prion diseases

PubMed abstracts associated with HSPA5

PMID Title Tumor Value
21573491 Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. no no
title all all