Results for HSPD1

General Information

Gene ID 3329
Gene Symbol HSPD1
Gene Name heat shock 60kDa protein 1 (chaperonin)
Gene Type protein-coding
Cytoband 2q33.1
Ensembl ID ENSG00000144381
#miR regulators 4
Omim ID 118190 605280 612233
Gene ontology GO:0002368: B cell cytokine production
GO:0002755: MyD88-dependent toll-like receptor signaling pathway
GO:0002842: positive regulation of T cell mediated immune response to tumor cell
GO:0006986: response to unfolded protein
GO:0042026: protein refolding
GO:0006200: ATP catabolic process
GO:0006458: 'de novo' protein folding
GO:0051131: chaperone-mediated protein complex assembly
GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043066: negative regulation of apoptotic process
GO:0050821: protein stabilization
GO:0019048: modulation by virus of host morphology or physiology
GO:0032727: positive regulation of interferon-alpha production
GO:0032729: positive regulation of interferon-gamma production
GO:0032733: positive regulation of interleukin-10 production
GO:0032735: positive regulation of interleukin-12 production
GO:0032755: positive regulation of interleukin-6 production
GO:0042100: B cell proliferation
GO:0042110: T cell activation
GO:0042113: B cell activation
GO:0043032: positive regulation of macrophage activation
GO:0043065: positive regulation of apoptotic process
GO:0048291: isotype switching to IgG isotypes
GO:0050870: positive regulation of T cell activation
GO:0051604: protein maturation
GO:0005886: plasma membrane
GO:0005739: mitochondrion
GO:0005829: cytosol
GO:0005615: extracellular space
GO:0005743: mitochondrial inner membrane
GO:0005759: mitochondrial matrix
GO:0005769: early endosome
GO:0030141: secretory granule
GO:0005905: coated pit
GO:0009986: cell surface
GO:0019907: cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0030135: coated vesicle
GO:0046696: lipopolysaccharide receptor complex
GO:0051082: unfolded protein binding
GO:0005515: protein binding
GO:0001530: lipopolysaccharide binding
GO:0002039: p53 binding
GO:0003688: DNA replication origin binding
GO:0003697: single-stranded DNA binding
GO:0051087: chaperone binding
GO:0005524: ATP binding
GO:0016887: ATPase activity
KEGG pathways 3018: RNA degradation
4940: Type I diabetes mellitus

PubMed abstracts associated with HSPD1

PMID Title Tumor Value
9781640 Heat shock protein 72 expression in osteosarcomas correlates with good response to neoadjuvant chemotherapy. yes yes
10776793 Serum antibodies against the heat shock protein 60 are elevated in patients with osteosarcoma. yes yes
11087053 Expression of heat shock proteins in osteosarcoma and its relationship to prognosis. yes yes
20632817 Expression of heat shock proteins in osteosarcomas. yes yes
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