General Information
| Gene ID | 3381 |
|---|---|
| Gene Symbol | IBSP |
| Gene Name | integrin-binding sialoprotein |
| Gene Type | protein-coding |
| Cytoband | 4q21.1 |
| Ensembl ID | ENSG00000029559 |
| #miR regulators | 5 |
| Omim ID | 147563 |
| Gene ontology |
GO:0001503: ossification GO:0007155: cell adhesion GO:0030198: extracellular matrix organization GO:0031214: biomineral tissue development GO:0071363: cellular response to growth factor stimulus GO:0005576: extracellular region |
| KEGG pathways |
4510: Focal adhesion 4512: ECM-receptor interaction |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 7794813 | Phenotypic modification of human osteosarcoma cells with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate. | no | no |
| 12232677 | Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces the osteoblastic differentiation of the human osteosarcoma cell line SaOS-2. | no | no |
| 12569382 | ErbB2 and bone sialoprotein as markers for metastatic osteosarcoma cells. | yes | yes |
| 14706926 | Effect of human granulocyte macrophage-colony stimulating factor on differentiation and apoptosis of the human osteosarcoma cell line SaOS-2. | no | no |
| 15516323 | Effect of TNF-alpha on human osteosarcoma cell line Saos2--TNF-alpha regulation of bone sialoprotein gene expression in Saos2 osteoblast-like cells. | no | no |
| 15946696 | Nicotine affects mineralized nodule formation by the human osteosarcoma cell line Saos-2. | no | no |
| 17956871 | Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression. | no | no |
| 20465837 | Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy. | yes | yes |
| title | all | all |