General Information
Gene ID | 3398 |
---|---|
Gene Symbol | ID2 |
Gene Name | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
Gene Type | protein-coding |
Cytoband | 2p25 |
Ensembl ID | ENSG00000115738 |
#miR regulators | 5 |
Omim ID | 600386 |
Gene ontology |
GO:0000122: negative regulation of transcription from RNA polymerase II promoter GO:0001656: metanephros development GO:0001779: natural killer cell differentiation GO:0003149: membranous septum morphogenesis GO:0003166: bundle of His development GO:0007275: multicellular organismal development GO:0009649: entrainment of circadian clock GO:0010628: positive regulation of gene expression GO:0010629: negative regulation of gene expression GO:0014003: oligodendrocyte development GO:0045893: positive regulation of transcription, DNA-dependent GO:0045892: negative regulation of transcription, DNA-dependent GO:0019216: regulation of lipid metabolic process GO:0021772: olfactory bulb development GO:0033598: mammary gland epithelial cell proliferation GO:0043353: enucleate erythrocyte differentiation GO:0043392: negative regulation of DNA binding GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity GO:0045578: negative regulation of B cell differentiation GO:0045600: positive regulation of fat cell differentiation GO:0045648: positive regulation of erythrocyte differentiation GO:0045651: positive regulation of macrophage differentiation GO:0045665: negative regulation of neuron differentiation GO:0045668: negative regulation of osteoblast differentiation GO:0045777: positive regulation of blood pressure GO:0045787: positive regulation of cell cycle GO:0048469: cell maturation GO:0048541: Peyer's patch development GO:0048557: embryonic digestive tract morphogenesis GO:0048661: positive regulation of smooth muscle cell proliferation GO:0048663: neuron fate commitment GO:0048711: positive regulation of astrocyte differentiation GO:0048715: negative regulation of oligodendrocyte differentiation GO:0060612: adipose tissue development GO:0060749: mammary gland alveolus development GO:0061030: epithelial cell differentiation involved in mammary gland alveolus development GO:0061031: endodermal digestive tract morphogenesis GO:0071158: positive regulation of cell cycle arrest GO:0071285: cellular response to lithium ion GO:0071931: positive regulation of transcription involved in G1/S phase of mitotic cell cycle GO:0090398: cellular senescence GO:2000045: regulation of G1/S transition of mitotic cell cycle GO:2000178: negative regulation of neural precursor cell proliferation GO:0000785: chromatin GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0043234: protein complex GO:0005515: protein binding GO:0046983: protein dimerization activity GO:0044325: ion channel binding |
KEGG pathways |
4350: TGF-beta signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
7926730 | The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein. | no | no |
15670817 | Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. | no | no |
21925315 | USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma. | no | no |
title | all | all |