Results for ID2

General Information

Gene ID 3398
Gene Symbol ID2
Gene Name inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Gene Type protein-coding
Cytoband 2p25
Ensembl ID ENSG00000115738
#miR regulators 5
Omim ID 600386
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001656: metanephros development
GO:0001779: natural killer cell differentiation
GO:0003149: membranous septum morphogenesis
GO:0003166: bundle of His development
GO:0007275: multicellular organismal development
GO:0009649: entrainment of circadian clock
GO:0010628: positive regulation of gene expression
GO:0010629: negative regulation of gene expression
GO:0014003: oligodendrocyte development
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0019216: regulation of lipid metabolic process
GO:0021772: olfactory bulb development
GO:0033598: mammary gland epithelial cell proliferation
GO:0043353: enucleate erythrocyte differentiation
GO:0043392: negative regulation of DNA binding
GO:0043433: negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045578: negative regulation of B cell differentiation
GO:0045600: positive regulation of fat cell differentiation
GO:0045648: positive regulation of erythrocyte differentiation
GO:0045651: positive regulation of macrophage differentiation
GO:0045665: negative regulation of neuron differentiation
GO:0045668: negative regulation of osteoblast differentiation
GO:0045777: positive regulation of blood pressure
GO:0045787: positive regulation of cell cycle
GO:0048469: cell maturation
GO:0048541: Peyer's patch development
GO:0048557: embryonic digestive tract morphogenesis
GO:0048661: positive regulation of smooth muscle cell proliferation
GO:0048663: neuron fate commitment
GO:0048711: positive regulation of astrocyte differentiation
GO:0048715: negative regulation of oligodendrocyte differentiation
GO:0060612: adipose tissue development
GO:0060749: mammary gland alveolus development
GO:0061030: epithelial cell differentiation involved in mammary gland alveolus development
GO:0061031: endodermal digestive tract morphogenesis
GO:0071158: positive regulation of cell cycle arrest
GO:0071285: cellular response to lithium ion
GO:0071931: positive regulation of transcription involved in G1/S phase of mitotic cell cycle
GO:0090398: cellular senescence
GO:2000045: regulation of G1/S transition of mitotic cell cycle
GO:2000178: negative regulation of neural precursor cell proliferation
GO:0000785: chromatin
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0043234: protein complex
GO:0005515: protein binding
GO:0046983: protein dimerization activity
GO:0044325: ion channel binding
KEGG pathways 4350: TGF-beta signaling pathway

PubMed abstracts associated with ID2

PMID Title Tumor Value
7926730 The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein. no no
15670817 Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells. no no
21925315 USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma. no no
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