General Information
| Gene ID | 3456 |
|---|---|
| Gene Symbol | IFNB1 |
| Gene Name | interferon, beta 1, fibroblast |
| Gene Type | protein-coding |
| Cytoband | 9p21 |
| Ensembl ID | ENSG00000171855 |
| #miR regulators | 1 |
| Omim ID | 147640 |
| Gene ontology |
GO:0002250: adaptive immune response GO:0042742: defense response to bacterium GO:0009615: response to virus GO:0007596: blood coagulation GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006959: humoral immune response GO:0007166: cell surface receptor signaling pathway GO:0008285: negative regulation of cell proliferation GO:0019221: cytokine-mediated signaling pathway GO:0030101: natural killer cell activation GO:0032897: negative regulation of viral transcription GO:0033141: positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0042100: B cell proliferation GO:0045071: negative regulation of viral genome replication GO:0045087: innate immune response GO:0045089: positive regulation of innate immune response GO:0045343: regulation of MHC class I biosynthetic process GO:0045581: negative regulation of T cell differentiation GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0046597: negative regulation of viral entry into host cell GO:0051607: defense response to virus GO:0060337: type I interferon-mediated signaling pathway GO:0060338: regulation of type I interferon-mediated signaling pathway GO:0071360: cellular response to exogenous dsRNA GO:0097194: execution phase of apoptosis GO:2000552: negative regulation of T-helper 2 cell cytokine production GO:0005576: extracellular region GO:0005615: extracellular space GO:0003714: transcription corepressor activity GO:0005125: cytokine activity GO:0005132: interferon-alpha/beta receptor binding |
| KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4380: Osteoclast differentiation 4620: Toll-like receptor signaling pathway 4622: RIG-I-like receptor signaling pathway 4623: Cytosolic DNA-sensing pathway 4630: Jak-STAT signaling pathway 4650: Natural killer cell mediated cytotoxicity 5142: Chagas disease (American trypanosomiasis) 5160: Hepatitis C |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 21411701 | Interferon-α/β receptor as a prognostic marker in osteosarcoma. | yes | yes |
| title | all | all |