Results for IFNB1

General Information

Gene ID 3456
Gene Symbol IFNB1
Gene Name interferon, beta 1, fibroblast
Gene Type protein-coding
Cytoband 9p21
Ensembl ID ENSG00000171855
#miR regulators 1
Omim ID 147640
Gene ontology GO:0002250: adaptive immune response
GO:0042742: defense response to bacterium
GO:0009615: response to virus
GO:0007596: blood coagulation
GO:0006919: activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006959: humoral immune response
GO:0007166: cell surface receptor signaling pathway
GO:0008285: negative regulation of cell proliferation
GO:0019221: cytokine-mediated signaling pathway
GO:0030101: natural killer cell activation
GO:0032897: negative regulation of viral transcription
GO:0033141: positive regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042100: B cell proliferation
GO:0045071: negative regulation of viral genome replication
GO:0045087: innate immune response
GO:0045089: positive regulation of innate immune response
GO:0045343: regulation of MHC class I biosynthetic process
GO:0045581: negative regulation of T cell differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0046597: negative regulation of viral entry into host cell
GO:0051607: defense response to virus
GO:0060337: type I interferon-mediated signaling pathway
GO:0060338: regulation of type I interferon-mediated signaling pathway
GO:0071360: cellular response to exogenous dsRNA
GO:0097194: execution phase of apoptosis
GO:2000552: negative regulation of T-helper 2 cell cytokine production
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0003714: transcription corepressor activity
GO:0005125: cytokine activity
GO:0005132: interferon-alpha/beta receptor binding
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4380: Osteoclast differentiation
4620: Toll-like receptor signaling pathway
4622: RIG-I-like receptor signaling pathway
4623: Cytosolic DNA-sensing pathway
4630: Jak-STAT signaling pathway
4650: Natural killer cell mediated cytotoxicity
5142: Chagas disease (American trypanosomiasis)
5160: Hepatitis C

PubMed abstracts associated with IFNB1

PMID Title Tumor Value
21411701 Interferon-α/β receptor as a prognostic marker in osteosarcoma. yes yes
title all all