Results for IGFBP5

General Information

Gene ID 3488
Gene Symbol IGFBP5
Gene Name insulin-like growth factor binding protein 5
Gene Type protein-coding
Cytoband 2q33-q36
Ensembl ID ENSG00000115461
#miR regulators 7
Omim ID 146734
Gene ontology GO:0001558: regulation of cell growth
GO:0001649: osteoblast differentiation
GO:0007165: signal transduction
GO:0035556: intracellular signal transduction
GO:0006006: glucose metabolic process
GO:0010906: regulation of glucose metabolic process
GO:0014912: negative regulation of smooth muscle cell migration
GO:0017148: negative regulation of translation
GO:0030336: negative regulation of cell migration
GO:0031069: hair follicle morphogenesis
GO:0042593: glucose homeostasis
GO:0043568: positive regulation of insulin-like growth factor receptor signaling pathway
GO:0043569: negative regulation of insulin-like growth factor receptor signaling pathway
GO:0044267: cellular protein metabolic process
GO:0044342: type B pancreatic cell proliferation
GO:0045668: negative regulation of osteoblast differentiation
GO:0048630: skeletal muscle tissue growth
GO:0048662: negative regulation of smooth muscle cell proliferation
GO:0051146: striated muscle cell differentiation
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0060056: mammary gland involution
GO:0071320: cellular response to cAMP
GO:0071407: cellular response to organic cyclic compound
GO:0005576: extracellular region
GO:0016942: insulin-like growth factor binding protein complex
GO:0005515: protein binding
GO:0001968: fibronectin binding
GO:0031994: insulin-like growth factor I binding
KEGG pathways ---

PubMed abstracts associated with IGFBP5

PMID Title Tumor Value
7684391 Regulation and biological effect of endogenous insulin-like growth factor binding protein-5 in human osteoblastic cells. no no
15095405 IGF-1 receptor contributes to the malignant phenotype in human and canine osteosarcoma. no no
16007340 Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation. no no
16269403 Identification and characterization of novel IGFBP5 interacting protein: evidence IGFBP5-IP is a potential regulator of osteoblast cell proliferation. no no
17372931 Alteration of the insulin-like growth factor axis during in vitro differentiation of the human osteosarcoma cell line HOS 58. no no
21460855 Insulin-like growth factor binding protein 5 suppresses tumor growth and metastasis of human osteosarcoma. yes no
title all all