Results for RBPJ

General Information

Gene ID 3516
Gene Symbol RBPJ
Gene Name recombination signal binding protein for immunoglobulin kappa J region
Gene Type protein-coding
Cytoband 4p15.2
Ensembl ID ENSG00000168214
#miR regulators 7
Omim ID 147183 614814
Gene ontology GO:0000122: negative regulation of transcription from RNA polymerase II promoter
GO:0001525: angiogenesis
GO:0001837: epithelial to mesenchymal transition
GO:0001974: blood vessel remodeling
GO:0002437: inflammatory response to antigenic stimulus
GO:0003151: outflow tract morphogenesis
GO:0003160: endocardium morphogenesis
GO:0003198: epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003214: cardiac left ventricle morphogenesis
GO:0003222: ventricular trabecula myocardium morphogenesis
GO:0003256: regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0042742: defense response to bacterium
GO:0006310: DNA recombination
GO:0006367: transcription initiation from RNA polymerase II promoter
GO:0006959: humoral immune response
GO:0007219: Notch signaling pathway
GO:0007221: positive regulation of transcription of Notch receptor target
GO:0008285: negative regulation of cell proliferation
GO:0009912: auditory receptor cell fate commitment
GO:0009957: epidermal cell fate specification
GO:0010467: gene expression
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0021983: pituitary gland development
GO:0030183: B cell differentiation
GO:0030216: keratinocyte differentiation
GO:0030279: negative regulation of ossification
GO:0030513: positive regulation of BMP signaling pathway
GO:0035019: somatic stem cell maintenance
GO:0035912: dorsal aorta morphogenesis
GO:0036302: atrioventricular canal development
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048505: regulation of timing of cell differentiation
GO:0048733: sebaceous gland development
GO:0048820: hair follicle maturation
GO:0060045: positive regulation of cardiac muscle cell proliferation
GO:0060716: labyrinthine layer blood vessel development
GO:0060844: arterial endothelial cell fate commitment
GO:0061314: Notch signaling involved in heart development
GO:0072554: blood vessel lumenization
GO:0072602: interleukin-4 secretion
GO:0097101: blood vessel endothelial cell fate specification
GO:1901186: positive regulation of ERBB signaling pathway
GO:1901189: positive regulation of ephrin receptor signaling pathway
GO:2000138: positive regulation of cell proliferation involved in heart morphogenesis
GO:0002193: MAML1-RBP-Jkappa- ICN1 complex
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005730: nucleolus
GO:0000150: recombinase activity
GO:0005515: protein binding
GO:0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding
GO:0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001103: RNA polymerase II repressing transcription factor binding
GO:0003677: DNA binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0047485: protein N-terminus binding
KEGG pathways 4330: Notch signaling pathway

PubMed abstracts associated with RBPJ

PMID Title Tumor Value
19455146 Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. no no
title all all