General Information
Gene ID | 3549 |
---|---|
Gene Symbol | IHH |
Gene Name | indian hedgehog |
Gene Type | protein-coding |
Cytoband | 2q33-q35 |
Ensembl ID | ENSG00000163501 |
#miR regulators | 8 |
Omim ID | 112500 600726 607778 |
Gene ontology |
GO:0001501: skeletal system development GO:0006029: proteoglycan metabolic process GO:0001569: patterning of blood vessels GO:0001649: osteoblast differentiation GO:0001701: in utero embryonic development GO:0001708: cell fate specification GO:0001947: heart looping GO:0002053: positive regulation of mesenchymal cell proliferation GO:0003382: epithelial cell morphogenesis GO:0003406: retinal pigment epithelium development GO:0006508: proteolysis GO:0007224: smoothened signaling pathway GO:0007267: cell-cell signaling GO:0009880: embryonic pattern specification GO:0016539: intein-mediated protein splicing GO:0030704: vitelline membrane formation GO:0031016: pancreas development GO:0032967: positive regulation of collagen biosynthetic process GO:0033085: negative regulation of T cell differentiation in thymus GO:0033088: negative regulation of immature T cell proliferation in thymus GO:0033089: positive regulation of T cell differentiation in thymus GO:0035264: multicellular organism growth GO:0035988: chondrocyte proliferation GO:0040008: regulation of growth GO:0045453: bone resorption GO:0045880: positive regulation of smoothened signaling pathway GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0046638: positive regulation of alpha-beta T cell differentiation GO:0046639: negative regulation of alpha-beta T cell differentiation GO:0048074: negative regulation of eye pigmentation GO:0048469: cell maturation GO:0048557: embryonic digestive tract morphogenesis GO:0048596: embryonic camera-type eye morphogenesis GO:0048666: neuron development GO:0048745: smooth muscle tissue development GO:0051216: cartilage development GO:0060220: camera-type eye photoreceptor cell fate commitment GO:0060323: head morphogenesis GO:0061053: somite development GO:0072498: embryonic skeletal joint development GO:0090136: epithelial cell-cell adhesion GO:0005886: plasma membrane GO:0005576: extracellular region GO:0005615: extracellular space GO:0031012: extracellular matrix GO:0005509: calcium ion binding GO:0008233: peptidase activity GO:0005113: patched binding |
KEGG pathways |
4340: Hedgehog signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
19688969 | Prognostic implication of immunohistochemical Runx2 expression in osteosarcoma. | yes | yes |
20067614 | Smoothened as a new therapeutic target for human osteosarcoma. | yes | no |
title | all | all |