General Information
Gene ID | 3551 |
---|---|
Gene Symbol | IKBKB |
Gene Name | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
Gene Type | protein-coding |
Cytoband | 8p11.2 |
Ensembl ID | ENSG00000104365 |
#miR regulators | 14 |
Omim ID | 603258 |
Gene ontology |
GO:0001782: B cell homeostasis GO:0002224: toll-like receptor signaling pathway GO:0002755: MyD88-dependent toll-like receptor signaling pathway GO:0002756: MyD88-independent toll-like receptor signaling pathway GO:0009615: response to virus GO:0006468: protein phosphorylation GO:0006954: inflammatory response GO:0007249: I-kappaB kinase/NF-kappaB cascade GO:0007252: I-kappaB phosphorylation GO:0043066: negative regulation of apoptotic process GO:0010765: positive regulation of sodium ion transport GO:0045893: positive regulation of transcription, DNA-dependent GO:0050852: T cell receptor signaling pathway GO:0032481: positive regulation of type I interferon production GO:0034134: toll-like receptor 2 signaling pathway GO:0034138: toll-like receptor 3 signaling pathway GO:0034142: toll-like receptor 4 signaling pathway GO:0034146: toll-like receptor 5 signaling pathway GO:0034162: toll-like receptor 9 signaling pathway GO:0034166: toll-like receptor 10 signaling pathway GO:0035666: TRIF-dependent toll-like receptor signaling pathway GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0038095: Fc-epsilon receptor signaling pathway GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0045087: innate immune response GO:0048011: neurotrophin TRK receptor signaling pathway GO:0051092: positive regulation of NF-kappaB transcription factor activity GO:0070423: nucleotide-binding oligomerization domain containing signaling pathway GO:2001259: positive regulation of cation channel activity GO:0005829: cytosol GO:0005634: nucleus GO:0008385: IkappaB kinase complex GO:0009898: internal side of plasma membrane GO:0035631: CD40 receptor complex GO:0045121: membrane raft GO:0005515: protein binding GO:0004672: protein kinase activity GO:0004674: protein serine/threonine kinase activity GO:0005524: ATP binding GO:0008384: IkappaB kinase activity GO:0042802: identical protein binding GO:0019901: protein kinase binding |
KEGG pathways |
4010: MAPK signaling pathway 4062: Chemokine signaling pathway 4210: Apoptosis 4380: Osteoclast differentiation 4620: Toll-like receptor signaling pathway 4621: NOD-like receptor signaling pathway 4622: RIG-I-like receptor signaling pathway 4623: Cytosolic DNA-sensing pathway 4660: T cell receptor signaling pathway 4662: B cell receptor signaling pathway 4722: Neurotrophin signaling pathway 4910: Insulin signaling pathway 4920: Adipocytokine signaling pathway 4930: Type II diabetes mellitus 5120: Epithelial cell signaling in Helicobacter pylori infection 5131: Shigellosis 5142: Chagas disease (American trypanosomiasis) 5145: Toxoplasmosis 5160: Hepatitis C 5200: Pathways in cancer 5212: Pancreatic cancer 5215: Prostate cancer 5220: Chronic myeloid leukemia 5221: Acute myeloid leukemia 5222: Small cell lung cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
17323424 | Human osteosarcoma cells express functional receptor activator of nuclear factor-kappa B. | no | no |
title | all | all |