Results for IKBKB

General Information

Gene ID 3551
Gene Symbol IKBKB
Gene Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene Type protein-coding
Cytoband 8p11.2
Ensembl ID ENSG00000104365
#miR regulators 14
Omim ID 603258
Gene ontology GO:0001782: B cell homeostasis
GO:0002224: toll-like receptor signaling pathway
GO:0002755: MyD88-dependent toll-like receptor signaling pathway
GO:0002756: MyD88-independent toll-like receptor signaling pathway
GO:0009615: response to virus
GO:0006468: protein phosphorylation
GO:0006954: inflammatory response
GO:0007249: I-kappaB kinase/NF-kappaB cascade
GO:0007252: I-kappaB phosphorylation
GO:0043066: negative regulation of apoptotic process
GO:0010765: positive regulation of sodium ion transport
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0050852: T cell receptor signaling pathway
GO:0032481: positive regulation of type I interferon production
GO:0034134: toll-like receptor 2 signaling pathway
GO:0034138: toll-like receptor 3 signaling pathway
GO:0034142: toll-like receptor 4 signaling pathway
GO:0034146: toll-like receptor 5 signaling pathway
GO:0034162: toll-like receptor 9 signaling pathway
GO:0034166: toll-like receptor 10 signaling pathway
GO:0035666: TRIF-dependent toll-like receptor signaling pathway
GO:0035872: nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095: Fc-epsilon receptor signaling pathway
GO:0038123: toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124: toll-like receptor TLR6:TLR2 signaling pathway
GO:0043123: positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045087: innate immune response
GO:0048011: neurotrophin TRK receptor signaling pathway
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0070423: nucleotide-binding oligomerization domain containing signaling pathway
GO:2001259: positive regulation of cation channel activity
GO:0005829: cytosol
GO:0005634: nucleus
GO:0008385: IkappaB kinase complex
GO:0009898: internal side of plasma membrane
GO:0035631: CD40 receptor complex
GO:0045121: membrane raft
GO:0005515: protein binding
GO:0004672: protein kinase activity
GO:0004674: protein serine/threonine kinase activity
GO:0005524: ATP binding
GO:0008384: IkappaB kinase activity
GO:0042802: identical protein binding
GO:0019901: protein kinase binding
KEGG pathways 4010: MAPK signaling pathway
4062: Chemokine signaling pathway
4210: Apoptosis
4380: Osteoclast differentiation
4620: Toll-like receptor signaling pathway
4621: NOD-like receptor signaling pathway
4622: RIG-I-like receptor signaling pathway
4623: Cytosolic DNA-sensing pathway
4660: T cell receptor signaling pathway
4662: B cell receptor signaling pathway
4722: Neurotrophin signaling pathway
4910: Insulin signaling pathway
4920: Adipocytokine signaling pathway
4930: Type II diabetes mellitus
5120: Epithelial cell signaling in Helicobacter pylori infection
5131: Shigellosis
5142: Chagas disease (American trypanosomiasis)
5145: Toxoplasmosis
5160: Hepatitis C
5200: Pathways in cancer
5212: Pancreatic cancer
5215: Prostate cancer
5220: Chronic myeloid leukemia
5221: Acute myeloid leukemia
5222: Small cell lung cancer

PubMed abstracts associated with IKBKB

PMID Title Tumor Value
17323424 Human osteosarcoma cells express functional receptor activator of nuclear factor-kappa B. no no
title all all