General Information
Gene ID | 3565 |
---|---|
Gene Symbol | IL4 |
Gene Name | interleukin 4 |
Gene Type | protein-coding |
Cytoband | 5q31.1 |
Ensembl ID | ENSG00000113520 |
#miR regulators | 1 |
Omim ID | 147780 |
Gene ontology |
GO:0002227: innate immune response in mucosa GO:0002296: T-helper 1 cell lineage commitment GO:0002674: negative regulation of acute inflammatory response GO:0002677: negative regulation of chronic inflammatory response GO:0006935: chemotaxis GO:0006955: immune response GO:0006968: cellular defense response GO:0007565: female pregnancy GO:0007584: response to nutrient GO:0043066: negative regulation of apoptotic process GO:0008203: cholesterol metabolic process GO:0042493: response to drug GO:0010155: regulation of proton transport GO:0014070: response to organic cyclic compound GO:0045893: positive regulation of transcription, DNA-dependent GO:0045892: negative regulation of transcription, DNA-dependent GO:0030183: B cell differentiation GO:0030890: positive regulation of B cell proliferation GO:0031296: B cell costimulation GO:0032733: positive regulation of interleukin-10 production GO:0032736: positive regulation of interleukin-13 production GO:0034097: response to cytokine stimulus GO:0035745: T-helper 2 cell cytokine production GO:0042092: type 2 immune response GO:0042102: positive regulation of T cell proliferation GO:0042104: positive regulation of activated T cell proliferation GO:0042325: regulation of phosphorylation GO:0042523: positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042832: defense response to protozoan GO:0043031: negative regulation of macrophage activation GO:0045019: negative regulation of nitric oxide biosynthetic process GO:0045064: T-helper 2 cell differentiation GO:0045080: positive regulation of chemokine biosynthetic process GO:0045189: connective tissue growth factor biosynthetic process GO:0045191: regulation of isotype switching GO:0045348: positive regulation of MHC class II biosynthetic process GO:0045471: response to ethanol GO:0045582: positive regulation of T cell differentiation GO:0045671: negative regulation of osteoclast differentiation GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0048295: positive regulation of isotype switching to IgE isotypes GO:0048304: positive regulation of isotype switching to IgG isotypes GO:0050776: regulation of immune response GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity GO:0071288: cellular response to mercury ion GO:0097028: dendritic cell differentiation GO:2000320: negative regulation of T-helper 17 cell differentiation GO:0005615: extracellular space GO:0009897: external side of plasma membrane GO:0005515: protein binding GO:0005125: cytokine activity GO:0005136: interleukin-4 receptor binding GO:0008083: growth factor activity |
KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4630: Jak-STAT signaling pathway 4640: Hematopoietic cell lineage 4660: T cell receptor signaling pathway 4664: Fc epsilon RI signaling pathway 4672: Intestinal immune network for IgA production 5140: Leishmaniasis 5310: Asthma 5320: Autoimmune thyroid disease 5330: Allograft rejection |
PMID | Title | Tumor | Value |
---|---|---|---|
9433149 | Recombinant human granulocyte-macrophage colony-stimulating factor therapy and endogenous plasma GM-CSF, IL-3, IL-4 concentrations in pediatric patients with solid tumors. | yes | no |
title | all | all |