Results for IL4

General Information

Gene ID 3565
Gene Symbol IL4
Gene Name interleukin 4
Gene Type protein-coding
Cytoband 5q31.1
Ensembl ID ENSG00000113520
#miR regulators 1
Omim ID 147780
Gene ontology GO:0002227: innate immune response in mucosa
GO:0002296: T-helper 1 cell lineage commitment
GO:0002674: negative regulation of acute inflammatory response
GO:0002677: negative regulation of chronic inflammatory response
GO:0006935: chemotaxis
GO:0006955: immune response
GO:0006968: cellular defense response
GO:0007565: female pregnancy
GO:0007584: response to nutrient
GO:0043066: negative regulation of apoptotic process
GO:0008203: cholesterol metabolic process
GO:0042493: response to drug
GO:0010155: regulation of proton transport
GO:0014070: response to organic cyclic compound
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0045892: negative regulation of transcription, DNA-dependent
GO:0030183: B cell differentiation
GO:0030890: positive regulation of B cell proliferation
GO:0031296: B cell costimulation
GO:0032733: positive regulation of interleukin-10 production
GO:0032736: positive regulation of interleukin-13 production
GO:0034097: response to cytokine stimulus
GO:0035745: T-helper 2 cell cytokine production
GO:0042092: type 2 immune response
GO:0042102: positive regulation of T cell proliferation
GO:0042104: positive regulation of activated T cell proliferation
GO:0042325: regulation of phosphorylation
GO:0042523: positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0042832: defense response to protozoan
GO:0043031: negative regulation of macrophage activation
GO:0045019: negative regulation of nitric oxide biosynthetic process
GO:0045064: T-helper 2 cell differentiation
GO:0045080: positive regulation of chemokine biosynthetic process
GO:0045189: connective tissue growth factor biosynthetic process
GO:0045191: regulation of isotype switching
GO:0045348: positive regulation of MHC class II biosynthetic process
GO:0045471: response to ethanol
GO:0045582: positive regulation of T cell differentiation
GO:0045671: negative regulation of osteoclast differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0048295: positive regulation of isotype switching to IgE isotypes
GO:0048304: positive regulation of isotype switching to IgG isotypes
GO:0050776: regulation of immune response
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0071288: cellular response to mercury ion
GO:0097028: dendritic cell differentiation
GO:2000320: negative regulation of T-helper 17 cell differentiation
GO:0005615: extracellular space
GO:0009897: external side of plasma membrane
GO:0005515: protein binding
GO:0005125: cytokine activity
GO:0005136: interleukin-4 receptor binding
GO:0008083: growth factor activity
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4630: Jak-STAT signaling pathway
4640: Hematopoietic cell lineage
4660: T cell receptor signaling pathway
4664: Fc epsilon RI signaling pathway
4672: Intestinal immune network for IgA production
5140: Leishmaniasis
5310: Asthma
5320: Autoimmune thyroid disease
5330: Allograft rejection

PubMed abstracts associated with IL4

PMID Title Tumor Value
9433149 Recombinant human granulocyte-macrophage colony-stimulating factor therapy and endogenous plasma GM-CSF, IL-3, IL-4 concentrations in pediatric patients with solid tumors. yes no
title all all