Results for IL8

General Information

Gene ID 3576
Gene Symbol IL8
Gene Name interleukin 8
Gene Type protein-coding
Cytoband 4q13-q21
Ensembl ID ENSG00000169429
#miR regulators 8
Omim ID 146930
Gene ontology GO:0001525: angiogenesis
GO:0002237: response to molecule of bacterial origin
GO:0007165: signal transduction
GO:0035556: intracellular signal transduction
GO:0006928: cellular component movement
GO:0006954: inflammatory response
GO:0006955: immune response
GO:0006987: activation of signaling protein activity involved in unfolded protein response
GO:0007050: cell cycle arrest
GO:0007186: G-protein coupled receptor signaling pathway
GO:0019722: calcium-mediated signaling
GO:0008285: negative regulation of cell proliferation
GO:0045744: negative regulation of G-protein coupled receptor protein signaling pathway
GO:0030155: regulation of cell adhesion
GO:0030593: neutrophil chemotaxis
GO:0030968: endoplasmic reticulum unfolded protein response
GO:0031623: receptor internalization
GO:0034976: response to endoplasmic reticulum stress
GO:0042119: neutrophil activation
GO:0044267: cellular protein metabolic process
GO:0044344: cellular response to fibroblast growth factor stimulus
GO:0045091: regulation of retroviral genome replication
GO:0048566: embryonic digestive tract development
GO:0050930: induction of positive chemotaxis
GO:0071222: cellular response to lipopolysaccharide
GO:0071347: cellular response to interleukin-1
GO:0071356: cellular response to tumor necrosis factor
GO:0090023: positive regulation of neutrophil chemotaxis
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005515: protein binding
GO:0005153: interleukin-8 receptor binding
GO:0008009: chemokine activity
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4062: Chemokine signaling pathway
4620: Toll-like receptor signaling pathway
4621: NOD-like receptor signaling pathway
4622: RIG-I-like receptor signaling pathway
5120: Epithelial cell signaling in Helicobacter pylori infection
5131: Shigellosis
5142: Chagas disease (American trypanosomiasis)
5144: Malaria
5146: Amoebiasis
5160: Hepatitis C
5200: Pathways in cancer
5219: Bladder cancer
5323: Rheumatoid arthritis

PubMed abstracts associated with IL8

PMID Title Tumor Value
14598359 Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. yes yes
18510171 Multiple pathways are involved in drug resistance to doxorubicin in an osteosarcoma cell line. no no
22641358 Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells. no no
title all all