Results for IL10

General Information

Gene ID 3586
Gene Symbol IL10
Gene Name interleukin 10
Gene Type protein-coding
Cytoband 1q31-q32
Ensembl ID ENSG00000136634
#miR regulators 2
Omim ID 124092 180300 609423 614395
Gene ontology GO:0002237: response to molecule of bacterial origin
GO:0002740: negative regulation of cytokine secretion involved in immune response
GO:0002875: negative regulation of chronic inflammatory response to antigenic stimulus
GO:0002904: positive regulation of B cell apoptotic process
GO:0042742: defense response to bacterium
GO:0006954: inflammatory response
GO:0007253: cytoplasmic sequestering of NF-kappaB
GO:0007267: cell-cell signaling
GO:0043066: negative regulation of apoptotic process
GO:0042493: response to drug
GO:0010468: regulation of gene expression
GO:0014823: response to activity
GO:0014854: response to inactivity
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0030097: hemopoiesis
GO:0030183: B cell differentiation
GO:0030595: leukocyte chemotaxis
GO:0030886: negative regulation of myeloid dendritic cell activation
GO:0030889: negative regulation of B cell proliferation
GO:0032689: negative regulation of interferon-gamma production
GO:0032695: negative regulation of interleukin-12 production
GO:0032715: negative regulation of interleukin-6 production
GO:0032720: negative regulation of tumor necrosis factor production
GO:0032800: receptor biosynthetic process
GO:0032868: response to insulin stimulus
GO:0044130: negative regulation of growth of symbiont in host
GO:0034465: response to carbon monoxide
GO:0042092: type 2 immune response
GO:0042100: B cell proliferation
GO:0042130: negative regulation of T cell proliferation
GO:0042536: negative regulation of tumor necrosis factor biosynthetic process
GO:0045019: negative regulation of nitric oxide biosynthetic process
GO:0045191: regulation of isotype switching
GO:0045347: negative regulation of MHC class II biosynthetic process
GO:0045348: positive regulation of MHC class II biosynthetic process
GO:0045355: negative regulation of interferon-alpha biosynthetic process
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0050715: positive regulation of cytokine secretion
GO:0051045: negative regulation of membrane protein ectodomain proteolysis
GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051384: response to glucocorticoid stimulus
GO:0051930: regulation of sensory perception of pain
GO:0060670: branching involved in labyrinthine layer morphogenesis
GO:0071222: cellular response to lipopolysaccharide
GO:0071392: cellular response to estradiol stimulus
GO:0005615: extracellular space
GO:0005125: cytokine activity
GO:0005141: interleukin-10 receptor binding
GO:0008083: growth factor activity
KEGG pathways 4060: Cytokine-cytokine receptor interaction
4630: Jak-STAT signaling pathway
4660: T cell receptor signaling pathway
4672: Intestinal immune network for IgA production
5140: Leishmaniasis
5142: Chagas disease (American trypanosomiasis)
5143: African trypanosomiasis
5144: Malaria
5145: Toxoplasmosis
5146: Amoebiasis
5150: Staphylococcus aureus infection
5310: Asthma
5320: Autoimmune thyroid disease
5322: Systemic lupus erythematosus
5330: Allograft rejection

PubMed abstracts associated with IL10

PMID Title Tumor Value
14598359 Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. yes yes
title all all