General Information
Gene ID | 3586 |
---|---|
Gene Symbol | IL10 |
Gene Name | interleukin 10 |
Gene Type | protein-coding |
Cytoband | 1q31-q32 |
Ensembl ID | ENSG00000136634 |
#miR regulators | 2 |
Omim ID | 124092 180300 609423 614395 |
Gene ontology |
GO:0002237: response to molecule of bacterial origin GO:0002740: negative regulation of cytokine secretion involved in immune response GO:0002875: negative regulation of chronic inflammatory response to antigenic stimulus GO:0002904: positive regulation of B cell apoptotic process GO:0042742: defense response to bacterium GO:0006954: inflammatory response GO:0007253: cytoplasmic sequestering of NF-kappaB GO:0007267: cell-cell signaling GO:0043066: negative regulation of apoptotic process GO:0042493: response to drug GO:0010468: regulation of gene expression GO:0014823: response to activity GO:0014854: response to inactivity GO:0045893: positive regulation of transcription, DNA-dependent GO:0030097: hemopoiesis GO:0030183: B cell differentiation GO:0030595: leukocyte chemotaxis GO:0030886: negative regulation of myeloid dendritic cell activation GO:0030889: negative regulation of B cell proliferation GO:0032689: negative regulation of interferon-gamma production GO:0032695: negative regulation of interleukin-12 production GO:0032715: negative regulation of interleukin-6 production GO:0032720: negative regulation of tumor necrosis factor production GO:0032800: receptor biosynthetic process GO:0032868: response to insulin stimulus GO:0044130: negative regulation of growth of symbiont in host GO:0034465: response to carbon monoxide GO:0042092: type 2 immune response GO:0042100: B cell proliferation GO:0042130: negative regulation of T cell proliferation GO:0042536: negative regulation of tumor necrosis factor biosynthetic process GO:0045019: negative regulation of nitric oxide biosynthetic process GO:0045191: regulation of isotype switching GO:0045347: negative regulation of MHC class II biosynthetic process GO:0045348: positive regulation of MHC class II biosynthetic process GO:0045355: negative regulation of interferon-alpha biosynthetic process GO:0045944: positive regulation of transcription from RNA polymerase II promoter GO:0050715: positive regulation of cytokine secretion GO:0051045: negative regulation of membrane protein ectodomain proteolysis GO:0051091: positive regulation of sequence-specific DNA binding transcription factor activity GO:0051384: response to glucocorticoid stimulus GO:0051930: regulation of sensory perception of pain GO:0060670: branching involved in labyrinthine layer morphogenesis GO:0071222: cellular response to lipopolysaccharide GO:0071392: cellular response to estradiol stimulus GO:0005615: extracellular space GO:0005125: cytokine activity GO:0005141: interleukin-10 receptor binding GO:0008083: growth factor activity |
KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4630: Jak-STAT signaling pathway 4660: T cell receptor signaling pathway 4672: Intestinal immune network for IgA production 5140: Leishmaniasis 5142: Chagas disease (American trypanosomiasis) 5143: African trypanosomiasis 5144: Malaria 5145: Toxoplasmosis 5146: Amoebiasis 5150: Staphylococcus aureus infection 5310: Asthma 5320: Autoimmune thyroid disease 5322: Systemic lupus erythematosus 5330: Allograft rejection |
PMID | Title | Tumor | Value |
---|---|---|---|
14598359 | Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. | yes | yes |
title | all | all |