General Information
| Gene ID | 3590 |
|---|---|
| Gene Symbol | IL11RA |
| Gene Name | interleukin 11 receptor, alpha |
| Gene Type | protein-coding |
| Cytoband | 9p13 |
| Ensembl ID | ENSG00000137070 |
| #miR regulators | 3 |
| Omim ID | 600939 614188 |
| Gene ontology |
GO:0007165: signal transduction GO:0032502: developmental process GO:0060322: head development GO:0005887: integral to plasma membrane GO:0004871: signal transducer activity GO:0004888: transmembrane signaling receptor activity GO:0004896: cytokine receptor activity |
| KEGG pathways |
4060: Cytokine-cytokine receptor interaction 4630: Jak-STAT signaling pathway 4640: Hematopoietic cell lineage |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 14598359 | Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. | yes | yes |
| 19244100 | The interleukin-11 receptor alpha as a candidate ligand-directed target in osteosarcoma: consistent data from cell lines, orthotopic models, and human tumor samples. | yes | no |
| 22075555 | Genetically modified T cells targeting interleukin-11 receptor α-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases. | yes | no |
| 23144859 | Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma. | yes | no |
| title | all | all |