Results for ILK

General Information

Gene ID 3611
Gene Symbol ILK
Gene Name integrin-linked kinase
Gene Type protein-coding
Cytoband 11p15.4
Ensembl ID ENSG00000166333
#miR regulators 1
Omim ID 602366
Gene ontology GO:0001658: branching involved in ureteric bud morphogenesis
GO:0001954: positive regulation of cell-matrix adhesion
GO:0006468: protein phosphorylation
GO:0006469: negative regulation of protein kinase activity
GO:0007050: cell cycle arrest
GO:0007160: cell-matrix adhesion
GO:0007229: integrin-mediated signaling pathway
GO:0007569: cell aging
GO:0008283: cell proliferation
GO:0008284: positive regulation of cell proliferation
GO:0010667: negative regulation of cardiac muscle cell apoptotic process
GO:0014912: negative regulation of smooth muscle cell migration
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0018105: peptidyl-serine phosphorylation
GO:0021675: nerve development
GO:0022011: myelination in peripheral nervous system
GO:0030335: positive regulation of cell migration
GO:0030513: positive regulation of BMP signaling pathway
GO:0032288: myelin assembly
GO:0032956: regulation of actin cytoskeleton organization
GO:0034329: cell junction assembly
GO:0034446: substrate adhesion-dependent cell spreading
GO:0042327: positive regulation of phosphorylation
GO:0043206: extracellular fibril organization
GO:0043406: positive regulation of MAP kinase activity
GO:0043491: protein kinase B signaling cascade
GO:0043524: negative regulation of neuron apoptotic process
GO:0045197: establishment or maintenance of epithelial cell apical/basal polarity
GO:0045663: positive regulation of myoblast differentiation
GO:0045669: positive regulation of osteoblast differentiation
GO:0045773: positive regulation of axon extension
GO:0048662: negative regulation of smooth muscle cell proliferation
GO:0048812: neuron projection morphogenesis
GO:0050775: positive regulation of dendrite morphogenesis
GO:0051291: protein heterooligomerization
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0090263: positive regulation of canonical Wnt receptor signaling pathway
GO:0005886: plasma membrane
GO:0005829: cytosol
GO:0005737: cytoplasm
GO:0005911: cell-cell junction
GO:0005925: focal adhesion
GO:0030017: sarcomere
GO:0030027: lamellipodium
GO:0043025: neuronal cell body
GO:0043034: costamere
GO:0043195: terminal bouton
GO:0043198: dendritic shaft
GO:0043234: protein complex
GO:0005515: protein binding
GO:0004674: protein serine/threonine kinase activity
GO:0004871: signal transducer activity
GO:0005178: integrin binding
GO:0005524: ATP binding
GO:0017124: SH3 domain binding
GO:0019901: protein kinase binding
KEGG pathways 3320: PPAR signaling pathway
4510: Focal adhesion
5100: Bacterial invasion of epithelial cells
5213: Endometrial cancer

PubMed abstracts associated with ILK

PMID Title Tumor Value
21145881 Nephroblastoma overexpressed gene (NOV) enhances cell motility and COX-2 upregulation of human osteosarcoma involves ?v?5 integrin, ILK and AP-1-dependent pathways. no no
22939995 IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma. yes no
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