Results for IMPDH2

General Information

Gene ID 3615
Gene Symbol IMPDH2
Gene Name IMP (inosine 5'-monophosphate) dehydrogenase 2
Gene Type protein-coding
Cytoband 3p21.2
Ensembl ID ENSG00000178035
#miR regulators ---
Omim ID 146691
Gene ontology GO:0006144: purine nucleobase metabolic process
GO:0006177: GMP biosynthetic process
GO:0009168: purine ribonucleoside monophosphate biosynthetic process
GO:0044281: small molecule metabolic process
GO:0046651: lymphocyte proliferation
GO:0051289: protein homotetramerization
GO:0055086: nucleobase-containing small molecule metabolic process
GO:0060041: retina development in camera-type eye
GO:0071353: cellular response to interleukin-4
GO:0005829: cytosol
GO:0005778: peroxisomal membrane
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0000166: nucleotide binding
GO:0003677: DNA binding
GO:0003723: RNA binding
GO:0003938: IMP dehydrogenase activity
GO:0046872: metal ion binding
GO:0030554: adenyl nucleotide binding
KEGG pathways 230: Purine metabolism
983: Drug metabolism - other enzymes
1100: Metabolic pathways

PubMed abstracts associated with IMPDH2

PMID Title Tumor Value
17660802 Prognostic significance of drug-regulated genes in high-grade osteosarcoma. yes yes
20808934 Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells. no no
title all all