General Information
Gene ID | 3615 |
---|---|
Gene Symbol | IMPDH2 |
Gene Name | IMP (inosine 5'-monophosphate) dehydrogenase 2 |
Gene Type | protein-coding |
Cytoband | 3p21.2 |
Ensembl ID | ENSG00000178035 |
#miR regulators | --- |
Omim ID | 146691 |
Gene ontology |
GO:0006144: purine nucleobase metabolic process GO:0006177: GMP biosynthetic process GO:0009168: purine ribonucleoside monophosphate biosynthetic process GO:0044281: small molecule metabolic process GO:0046651: lymphocyte proliferation GO:0051289: protein homotetramerization GO:0055086: nucleobase-containing small molecule metabolic process GO:0060041: retina development in camera-type eye GO:0071353: cellular response to interleukin-4 GO:0005829: cytosol GO:0005778: peroxisomal membrane GO:0005634: nucleus GO:0005737: cytoplasm GO:0000166: nucleotide binding GO:0003677: DNA binding GO:0003723: RNA binding GO:0003938: IMP dehydrogenase activity GO:0046872: metal ion binding GO:0030554: adenyl nucleotide binding |
KEGG pathways |
230: Purine metabolism 983: Drug metabolism - other enzymes 1100: Metabolic pathways |
PMID | Title | Tumor | Value |
---|---|---|---|
17660802 | Prognostic significance of drug-regulated genes in high-grade osteosarcoma. | yes | yes |
20808934 | Overexpression of inosine 5'-monophosphate dehydrogenase type II mediates chemoresistance to human osteosarcoma cells. | no | no |
title | all | all |