General Information
Gene ID | 3630 |
---|---|
Gene Symbol | INS |
Gene Name | insulin |
Gene Type | protein-coding |
Cytoband | 11p15.5 |
Ensembl ID | ENSG00000254647 |
#miR regulators | --- |
Omim ID | 125852 176730 606176 613370 |
Gene ontology |
GO:0000165: MAPK cascade GO:0002674: negative regulation of acute inflammatory response GO:0006953: acute-phase response GO:0006006: glucose metabolic process GO:0006112: energy reserve metabolic process GO:0006355: regulation of transcription, DNA-dependent GO:0006521: regulation of cellular amino acid metabolic process GO:0007186: G-protein coupled receptor signaling pathway GO:0007267: cell-cell signaling GO:0050796: regulation of insulin secretion GO:0008284: positive regulation of cell proliferation GO:0008286: insulin receptor signaling pathway GO:0045909: positive regulation of vasodilation GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade GO:0015758: glucose transport GO:0046326: positive regulation of glucose import GO:0046889: positive regulation of lipid biosynthetic process GO:0022898: regulation of transmembrane transporter activity GO:0030307: positive regulation of cell growth GO:0030335: positive regulation of cell migration GO:0031018: endocrine pancreas development GO:0031954: positive regulation of protein autophosphorylation GO:0032148: activation of protein kinase B activity GO:0032270: positive regulation of cellular protein metabolic process GO:0032460: negative regulation of protein oligomerization GO:0032880: regulation of protein localization GO:0033861: negative regulation of NAD(P)H oxidase activity GO:0042060: wound healing GO:0042177: negative regulation of protein catabolic process GO:0042593: glucose homeostasis GO:0043410: positive regulation of MAPK cascade GO:0044267: cellular protein metabolic process GO:0044281: small molecule metabolic process GO:0045429: positive regulation of nitric oxide biosynthetic process GO:0045597: positive regulation of cell differentiation GO:0045721: negative regulation of gluconeogenesis GO:0045725: positive regulation of glycogen biosynthetic process GO:0045740: positive regulation of DNA replication GO:0045818: negative regulation of glycogen catabolic process GO:0045821: positive regulation of glycolysis GO:0045840: positive regulation of mitosis GO:0045861: negative regulation of proteolysis GO:0045908: negative regulation of vasodilation GO:0045922: negative regulation of fatty acid metabolic process GO:0046628: positive regulation of insulin receptor signaling pathway GO:0046631: alpha-beta T cell activation GO:0050708: regulation of protein secretion GO:0050709: negative regulation of protein secretion GO:0050715: positive regulation of cytokine secretion GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation GO:0050995: negative regulation of lipid catabolic process GO:0051000: positive regulation of nitric-oxide synthase activity GO:0051092: positive regulation of NF-kappaB transcription factor activity GO:0051897: positive regulation of protein kinase B signaling cascade GO:0055089: fatty acid homeostasis GO:0060266: negative regulation of respiratory burst involved in inflammatory response GO:0060267: positive regulation of respiratory burst GO:0090277: positive regulation of peptide hormone secretion GO:0090336: positive regulation of brown fat cell differentiation GO:1902176: negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress GO:2000252: negative regulation of feeding behavior GO:0005576: extracellular region GO:0005615: extracellular space GO:0005788: endoplasmic reticulum lumen GO:0005796: Golgi lumen GO:0031904: endosome lumen GO:0034774: secretory granule lumen GO:0005515: protein binding GO:0002020: protease binding GO:0005158: insulin receptor binding GO:0005159: insulin-like growth factor receptor binding GO:0005179: hormone activity |
KEGG pathways |
4114: Oocyte meiosis 4140: Regulation of autophagy 4150: mTOR signaling pathway 4810: Regulation of actin cytoskeleton 4910: Insulin signaling pathway 4914: Progesterone-mediated oocyte maturation 4930: Type II diabetes mellitus 4940: Type I diabetes mellitus 4950: Maturity onset diabetes of the young 4960: Aldosterone-regulated sodium reabsorption 5215: Prostate cancer |
PMID | Title | Tumor | Value |
---|---|---|---|
21321933 | Insulin regulates GLUT1-mediated glucose transport in MG-63 human osteosarcoma cells. | yes | no |
title | all | all |