Results for INS

General Information

Gene ID 3630
Gene Symbol INS
Gene Name insulin
Gene Type protein-coding
Cytoband 11p15.5
Ensembl ID ENSG00000254647
#miR regulators ---
Omim ID 125852 176730 606176 613370
Gene ontology GO:0000165: MAPK cascade
GO:0002674: negative regulation of acute inflammatory response
GO:0006953: acute-phase response
GO:0006006: glucose metabolic process
GO:0006112: energy reserve metabolic process
GO:0006355: regulation of transcription, DNA-dependent
GO:0006521: regulation of cellular amino acid metabolic process
GO:0007186: G-protein coupled receptor signaling pathway
GO:0007267: cell-cell signaling
GO:0050796: regulation of insulin secretion
GO:0008284: positive regulation of cell proliferation
GO:0008286: insulin receptor signaling pathway
GO:0045909: positive regulation of vasodilation
GO:0014068: positive regulation of phosphatidylinositol 3-kinase cascade
GO:0015758: glucose transport
GO:0046326: positive regulation of glucose import
GO:0046889: positive regulation of lipid biosynthetic process
GO:0022898: regulation of transmembrane transporter activity
GO:0030307: positive regulation of cell growth
GO:0030335: positive regulation of cell migration
GO:0031018: endocrine pancreas development
GO:0031954: positive regulation of protein autophosphorylation
GO:0032148: activation of protein kinase B activity
GO:0032270: positive regulation of cellular protein metabolic process
GO:0032460: negative regulation of protein oligomerization
GO:0032880: regulation of protein localization
GO:0033861: negative regulation of NAD(P)H oxidase activity
GO:0042060: wound healing
GO:0042177: negative regulation of protein catabolic process
GO:0042593: glucose homeostasis
GO:0043410: positive regulation of MAPK cascade
GO:0044267: cellular protein metabolic process
GO:0044281: small molecule metabolic process
GO:0045429: positive regulation of nitric oxide biosynthetic process
GO:0045597: positive regulation of cell differentiation
GO:0045721: negative regulation of gluconeogenesis
GO:0045725: positive regulation of glycogen biosynthetic process
GO:0045740: positive regulation of DNA replication
GO:0045818: negative regulation of glycogen catabolic process
GO:0045821: positive regulation of glycolysis
GO:0045840: positive regulation of mitosis
GO:0045861: negative regulation of proteolysis
GO:0045908: negative regulation of vasodilation
GO:0045922: negative regulation of fatty acid metabolic process
GO:0046628: positive regulation of insulin receptor signaling pathway
GO:0046631: alpha-beta T cell activation
GO:0050708: regulation of protein secretion
GO:0050709: negative regulation of protein secretion
GO:0050715: positive regulation of cytokine secretion
GO:0050731: positive regulation of peptidyl-tyrosine phosphorylation
GO:0050995: negative regulation of lipid catabolic process
GO:0051000: positive regulation of nitric-oxide synthase activity
GO:0051092: positive regulation of NF-kappaB transcription factor activity
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0055089: fatty acid homeostasis
GO:0060266: negative regulation of respiratory burst involved in inflammatory response
GO:0060267: positive regulation of respiratory burst
GO:0090277: positive regulation of peptide hormone secretion
GO:0090336: positive regulation of brown fat cell differentiation
GO:1902176: negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress
GO:2000252: negative regulation of feeding behavior
GO:0005576: extracellular region
GO:0005615: extracellular space
GO:0005788: endoplasmic reticulum lumen
GO:0005796: Golgi lumen
GO:0031904: endosome lumen
GO:0034774: secretory granule lumen
GO:0005515: protein binding
GO:0002020: protease binding
GO:0005158: insulin receptor binding
GO:0005159: insulin-like growth factor receptor binding
GO:0005179: hormone activity
KEGG pathways 4114: Oocyte meiosis
4140: Regulation of autophagy
4150: mTOR signaling pathway
4810: Regulation of actin cytoskeleton
4910: Insulin signaling pathway
4914: Progesterone-mediated oocyte maturation
4930: Type II diabetes mellitus
4940: Type I diabetes mellitus
4950: Maturity onset diabetes of the young
4960: Aldosterone-regulated sodium reabsorption
5215: Prostate cancer

PubMed abstracts associated with INS

PMID Title Tumor Value
21321933 Insulin regulates GLUT1-mediated glucose transport in MG-63 human osteosarcoma cells. yes no
title all all