Results for INSR

General Information

Gene ID 3643
Gene Symbol INSR
Gene Name insulin receptor
Gene Type protein-coding
Cytoband 19p13.3-p13.2
Ensembl ID ENSG00000171105
#miR regulators 16
Omim ID 147670 246200 262190 609968 610549
Gene ontology GO:0000187: activation of MAPK activity
GO:0001934: positive regulation of protein phosphorylation
GO:0003007: heart morphogenesis
GO:0005975: carbohydrate metabolic process
GO:0006355: regulation of transcription, DNA-dependent
GO:0007186: G-protein coupled receptor signaling pathway
GO:0008284: positive regulation of cell proliferation
GO:0008286: insulin receptor signaling pathway
GO:0046326: positive regulation of glucose import
GO:0018108: peptidyl-tyrosine phosphorylation
GO:0019087: transformation of host cell by virus
GO:0023014: signal transduction by phosphorylation
GO:0030238: male sex determination
GO:0030335: positive regulation of cell migration
GO:0031017: exocrine pancreas development
GO:0032147: activation of protein kinase activity
GO:0032148: activation of protein kinase B activity
GO:0032869: cellular response to insulin stimulus
GO:0042593: glucose homeostasis
GO:0043410: positive regulation of MAPK cascade
GO:0045429: positive regulation of nitric oxide biosynthetic process
GO:0045725: positive regulation of glycogen biosynthetic process
GO:0045740: positive regulation of DNA replication
GO:0045821: positive regulation of glycolysis
GO:0045840: positive regulation of mitosis
GO:0045995: regulation of embryonic development
GO:0046777: protein autophosphorylation
GO:0048639: positive regulation of developmental growth
GO:0051290: protein heterotetramerization
GO:0051897: positive regulation of protein kinase B signaling cascade
GO:0060267: positive regulation of respiratory burst
GO:0071363: cellular response to growth factor stimulus
GO:0005886: plasma membrane
GO:0016020: membrane
GO:0005887: integral to plasma membrane
GO:0005899: insulin receptor complex
GO:0005901: caveola
GO:0010008: endosome membrane
GO:0005515: protein binding
GO:0004713: protein tyrosine kinase activity
GO:0004716: receptor signaling protein tyrosine kinase activity
GO:0005009: insulin-activated receptor activity
GO:0005159: insulin-like growth factor receptor binding
GO:0005524: ATP binding
GO:0005525: GTP binding
GO:0031994: insulin-like growth factor I binding
GO:0031995: insulin-like growth factor II binding
GO:0042169: SH2 domain binding
GO:0043548: phosphatidylinositol 3-kinase binding
GO:0043559: insulin binding
GO:0043560: insulin receptor substrate binding
GO:0051425: PTB domain binding
KEGG pathways 4520: Adherens junction
4910: Insulin signaling pathway
4930: Type II diabetes mellitus
4960: Aldosterone-regulated sodium reabsorption

PubMed abstracts associated with INSR

PMID Title Tumor Value
19258511 Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma. yes no
21751203 Cell surface receptor expression patterns in osteosarcoma. yes no
title all all