Results for ITGA3

General Information

Gene ID 3675
Gene Symbol ITGA3
Gene Name integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Gene Type protein-coding
Cytoband 17q21.33
Ensembl ID ENSG00000005884
#miR regulators 8
Omim ID 605025 614748
Gene ontology GO:0001764: neuron migration
GO:0007596: blood coagulation
GO:0007160: cell-matrix adhesion
GO:0007229: integrin-mediated signaling pathway
GO:0007613: memory
GO:0050900: leukocyte migration
GO:0005886: plasma membrane
GO:0008305: integrin complex
GO:0009986: cell surface
GO:0016323: basolateral plasma membrane
GO:0045202: synapse
GO:0005515: protein binding
GO:0046872: metal ion binding
KEGG pathways 4510: Focal adhesion
4512: ECM-receptor interaction
4640: Hematopoietic cell lineage
4810: Regulation of actin cytoskeleton
5200: Pathways in cancer
5222: Small cell lung cancer
5410: Hypertrophic cardiomyopathy (HCM)
5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC)
5414: Dilated cardiomyopathy

PubMed abstracts associated with ITGA3

PMID Title Tumor Value
2600089 Transforming growth factor-beta switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. no no
16878156 Cooperation between Myc and YY1 provides novel silencing transcriptional targets of alpha3beta1-integrin in tumour cells. no no
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