General Information
| Gene ID | 3675 |
|---|---|
| Gene Symbol | ITGA3 |
| Gene Name | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| Gene Type | protein-coding |
| Cytoband | 17q21.33 |
| Ensembl ID | ENSG00000005884 |
| #miR regulators | 8 |
| Omim ID | 605025 614748 |
| Gene ontology |
GO:0001764: neuron migration GO:0007596: blood coagulation GO:0007160: cell-matrix adhesion GO:0007229: integrin-mediated signaling pathway GO:0007613: memory GO:0050900: leukocyte migration GO:0005886: plasma membrane GO:0008305: integrin complex GO:0009986: cell surface GO:0016323: basolateral plasma membrane GO:0045202: synapse GO:0005515: protein binding GO:0046872: metal ion binding |
| KEGG pathways |
4510: Focal adhesion 4512: ECM-receptor interaction 4640: Hematopoietic cell lineage 4810: Regulation of actin cytoskeleton 5200: Pathways in cancer 5222: Small cell lung cancer 5410: Hypertrophic cardiomyopathy (HCM) 5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5414: Dilated cardiomyopathy |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 2600089 | Transforming growth factor-beta switches the pattern of integrins expressed in MG-63 human osteosarcoma cells and causes a selective loss of cell adhesion to laminin. | no | no |
| 16878156 | Cooperation between Myc and YY1 provides novel silencing transcriptional targets of alpha3beta1-integrin in tumour cells. | no | no |
| title | all | all |