Results for ITGB5

General Information

Gene ID 3693
Gene Symbol ITGB5
Gene Name integrin, beta 5
Gene Type protein-coding
Cytoband 3q21.2
Ensembl ID ENSG00000082781
#miR regulators 5
Omim ID 147561
Gene ontology GO:0002474: antigen processing and presentation of peptide antigen via MHC class I
GO:0002479: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006936: muscle contraction
GO:0007155: cell adhesion
GO:0007229: integrin-mediated signaling pathway
GO:0007275: multicellular organismal development
GO:0030198: extracellular matrix organization
GO:0042590: antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0005886: plasma membrane
GO:0008305: integrin complex
GO:0005925: focal adhesion
GO:0031252: cell leading edge
GO:0045335: phagocytic vesicle
GO:0005515: protein binding
GO:0004872: receptor activity
GO:0005178: integrin binding
KEGG pathways 4145: Phagosome
4510: Focal adhesion
4512: ECM-receptor interaction
4810: Regulation of actin cytoskeleton
5410: Hypertrophic cardiomyopathy (HCM)
5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC)
5414: Dilated cardiomyopathy

PubMed abstracts associated with ITGB5

PMID Title Tumor Value
18445685 PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alphavbeta5 and alpha5beta1 integrins. yes no
21145881 Nephroblastoma overexpressed gene (NOV) enhances cell motility and COX-2 upregulation of human osteosarcoma involves αvβ5 integrin, ILK and AP-1-dependent pathways. no no
title all all