General Information
| Gene ID | 3693 |
|---|---|
| Gene Symbol | ITGB5 |
| Gene Name | integrin, beta 5 |
| Gene Type | protein-coding |
| Cytoband | 3q21.2 |
| Ensembl ID | ENSG00000082781 |
| #miR regulators | 5 |
| Omim ID | 147561 |
| Gene ontology |
GO:0002474: antigen processing and presentation of peptide antigen via MHC class I GO:0002479: antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0006936: muscle contraction GO:0007155: cell adhesion GO:0007229: integrin-mediated signaling pathway GO:0007275: multicellular organismal development GO:0030198: extracellular matrix organization GO:0042590: antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0005886: plasma membrane GO:0008305: integrin complex GO:0005925: focal adhesion GO:0031252: cell leading edge GO:0045335: phagocytic vesicle GO:0005515: protein binding GO:0004872: receptor activity GO:0005178: integrin binding |
| KEGG pathways |
4145: Phagosome 4510: Focal adhesion 4512: ECM-receptor interaction 4810: Regulation of actin cytoskeleton 5410: Hypertrophic cardiomyopathy (HCM) 5412: Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5414: Dilated cardiomyopathy |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 18445685 | PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the alphavbeta5 and alpha5beta1 integrins. | yes | no |
| 21145881 | Nephroblastoma overexpressed gene (NOV) enhances cell motility and COX-2 upregulation of human osteosarcoma involves αvβ5 integrin, ILK and AP-1-dependent pathways. | no | no |
| title | all | all |