General Information
Gene ID | 3827 |
---|---|
Gene Symbol | KNG1 |
Gene Name | kininogen 1 |
Gene Type | protein-coding |
Cytoband | 3q27 |
Ensembl ID | ENSG00000113889 |
#miR regulators | 14 |
Omim ID | 228960 612358 |
Gene ontology |
GO:0002576: platelet degranulation GO:0035815: positive regulation of renal sodium excretion GO:0035810: positive regulation of urine volume GO:0007596: blood coagulation GO:0006939: smooth muscle contraction GO:0006954: inflammatory response GO:0007162: negative regulation of cell adhesion GO:0007204: elevation of cytosolic calcium ion concentration GO:0007597: blood coagulation, intrinsic pathway GO:0030168: platelet activation GO:0030195: negative regulation of blood coagulation GO:0042311: vasodilation GO:0043065: positive regulation of apoptotic process GO:0005886: plasma membrane GO:0005576: extracellular region GO:0005615: extracellular space GO:0031093: platelet alpha granule lumen GO:0005515: protein binding GO:0005102: receptor binding GO:0004869: cysteine-type endopeptidase inhibitor activity GO:0008201: heparin binding GO:0008270: zinc ion binding |
KEGG pathways |
4610: Complement and coagulation cascades |
PMID | Title | Tumor | Value |
---|---|---|---|
11689005 | Inhibition of vitronectin-mediated haptotaxis and haptoinvasion of MG-63 cells by domain 5 (D5(H)) of human high-molecular-weight kininogen and identification of a minimal amino acid sequence. | no | no |
23000411 | Domain 5 of high molecular weight kininogen inhibits collagen-mediated cancer cell adhesion and invasion in association with α-actinin-4. | no | no |
title | all | all |