General Information
| Gene ID | 3984 |
|---|---|
| Gene Symbol | LIMK1 |
| Gene Name | LIM domain kinase 1 |
| Gene Type | protein-coding |
| Cytoband | 7q11.23 |
| Ensembl ID | ENSG00000106683 ENSG00000269943 ENSG00000262063 ENSG00000269917 |
| #miR regulators | 11 |
| Omim ID | 601329 |
| Gene ontology |
GO:0030036: actin cytoskeleton organization GO:0007165: signal transduction GO:0006468: protein phosphorylation GO:0007266: Rho protein signal transduction GO:0007399: nervous system development GO:0007411: axon guidance GO:0032233: positive regulation of actin filament bundle assembly GO:0038096: Fc-gamma receptor signaling pathway involved in phagocytosis GO:0045087: innate immune response GO:0045773: positive regulation of axon extension GO:0051444: negative regulation of ubiquitin-protein ligase activity GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0043005: neuron projection GO:0005515: protein binding GO:0004672: protein kinase activity GO:0004674: protein serine/threonine kinase activity GO:0005524: ATP binding GO:0008270: zinc ion binding GO:0031072: heat shock protein binding |
| KEGG pathways |
4360: Axon guidance 4666: Fc gamma R-mediated phagocytosis 4810: Regulation of actin cytoskeleton |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 22715593 | Overexpression of LIMK1 promotes migration ability of multidrug-resistant osteosarcoma cells. | no | no |
| title | all | all |