General Information
| Gene ID | 4035 |
|---|---|
| Gene Symbol | LRP1 |
| Gene Name | low density lipoprotein receptor-related protein 1 |
| Gene Type | protein-coding |
| Cytoband | 12q13.3 |
| Ensembl ID | ENSG00000123384 |
| #miR regulators | 3 |
| Omim ID | 107770 |
| Gene ontology |
GO:0001523: retinoid metabolic process GO:0006898: receptor-mediated endocytosis GO:0007603: phototransduction, visible light GO:0008203: cholesterol metabolic process GO:0010875: positive regulation of cholesterol efflux GO:0014912: negative regulation of smooth muscle cell migration GO:0030178: negative regulation of Wnt receptor signaling pathway GO:0032370: positive regulation of lipid transport GO:0032374: regulation of cholesterol transport GO:0032429: regulation of phospholipase A2 activity GO:0032956: regulation of actin cytoskeleton organization GO:0035909: aorta morphogenesis GO:0042953: lipoprotein transport GO:0043277: apoptotic cell clearance GO:0097242: beta-amyloid clearance GO:2000587: negative regulation of platelet-derived growth factor receptor-beta signaling pathway GO:0005886: plasma membrane GO:0005887: integral to plasma membrane GO:0005634: nucleus GO:0005905: coated pit GO:0030666: endocytic vesicle membrane GO:0005515: protein binding GO:0005509: calcium ion binding GO:0004872: receptor activity GO:0032403: protein complex binding GO:0034185: apolipoprotein binding GO:0042954: lipoprotein transporter activity GO:0070325: lipoprotein particle receptor binding |
| KEGG pathways |
5010: Alzheimer's disease 5144: Malaria |
| PMID | Title | Tumor | Value |
|---|---|---|---|
| 8117620 | Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2. | yes | no |
| title | all | all |