Results for SMAD1

General Information

Gene ID 4086
Gene Symbol SMAD1
Gene Name SMAD family member 1
Gene Type protein-coding
Cytoband 4q31
Ensembl ID ENSG00000170365
#miR regulators 12
Omim ID 601595
Gene ontology GO:0000165: MAPK cascade
GO:0001657: ureteric bud development
GO:0001710: mesodermal cell fate commitment
GO:0001822: kidney development
GO:0002051: osteoblast fate commitment
GO:0007165: signal transduction
GO:0006351: transcription, DNA-dependent
GO:0006468: protein phosphorylation
GO:0006954: inflammatory response
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0007183: SMAD protein complex assembly
GO:0007276: gamete generation
GO:0009880: embryonic pattern specification
GO:0008285: negative regulation of cell proliferation
GO:0042493: response to drug
GO:0010243: response to organonitrogen compound
GO:0010628: positive regulation of gene expression
GO:0030509: BMP signaling pathway
GO:0030901: midbrain development
GO:0030902: hindbrain development
GO:0031053: primary miRNA processing
GO:0042060: wound healing
GO:0042592: homeostatic process
GO:0045669: positive regulation of osteoblast differentiation
GO:0045944: positive regulation of transcription from RNA polymerase II promoter
GO:0050775: positive regulation of dendrite morphogenesis
GO:0051216: cartilage development
GO:0060038: cardiac muscle cell proliferation
GO:0060348: bone development
GO:0061036: positive regulation of cartilage development
GO:0071773: cellular response to BMP stimulus
GO:1901522: positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:0005622: intracellular
GO:0016021: integral to membrane
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005637: nuclear inner membrane
GO:0005737: cytoplasm
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0005057: receptor signaling protein activity
GO:0030618: transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0046872: metal ion binding
GO:0042802: identical protein binding
GO:0019901: protein kinase binding
GO:0070410: co-SMAD binding
GO:0070411: I-SMAD binding
KEGG pathways 4350: TGF-beta signaling pathway

PubMed abstracts associated with SMAD1

PMID Title Tumor Value
15174116 Differential expression of osteogenic factors associated with osteoinductivity of human osteosarcoma cell lines. no no
23262982 Preventing MEK1 activation influences the responses of human osteosarcoma cells to bone morphogenetic proteins 2 and 9. no no
title all all