Results for SMAD5

General Information

Gene ID 4090
Gene Symbol SMAD5
Gene Name SMAD family member 5
Gene Type protein-coding
Cytoband 5q31
Ensembl ID ENSG00000113658
#miR regulators 25
Omim ID 603110
Gene ontology GO:0001657: ureteric bud development
GO:0001880: Mullerian duct regression
GO:0002051: osteoblast fate commitment
GO:0007165: signal transduction
GO:0006351: transcription, DNA-dependent
GO:0006468: protein phosphorylation
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0007281: germ cell development
GO:0009880: embryonic pattern specification
GO:0045893: positive regulation of transcription, DNA-dependent
GO:0030218: erythrocyte differentiation
GO:0030509: BMP signaling pathway
GO:0045669: positive regulation of osteoblast differentiation
GO:0051216: cartilage development
GO:0060048: cardiac muscle contraction
GO:0060348: bone development
GO:0071407: cellular response to organic cyclic compound
GO:0071773: cellular response to BMP stimulus
GO:1901522: positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:0005622: intracellular
GO:0016021: integral to membrane
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005654: nucleoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0000979: RNA polymerase II core promoter sequence-specific DNA binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0005057: receptor signaling protein activity
GO:0030618: transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0046872: metal ion binding
GO:0031625: ubiquitin protein ligase binding
KEGG pathways 4350: TGF-beta signaling pathway

PubMed abstracts associated with SMAD5

PMID Title Tumor Value
15174116 Differential expression of osteogenic factors associated with osteoinductivity of human osteosarcoma cell lines. no no
23262982 Preventing MEK1 activation influences the responses of human osteosarcoma cells to bone morphogenetic proteins 2 and 9. no no
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