General Information
Gene ID | 4091 |
---|---|
Gene Symbol | SMAD6 |
Gene Name | SMAD family member 6 |
Gene Type | protein-coding |
Cytoband | 15q21-q22 |
Ensembl ID | ENSG00000137834 |
#miR regulators | 7 |
Omim ID | 602931 614823 |
Gene ontology |
GO:0001657: ureteric bud development GO:0006351: transcription, DNA-dependent GO:0006955: immune response GO:0007179: transforming growth factor beta receptor signaling pathway GO:0007352: zygotic specification of dorsal/ventral axis GO:0043066: negative regulation of apoptotic process GO:0008285: negative regulation of cell proliferation GO:0010991: negative regulation of SMAD protein complex assembly GO:0030509: BMP signaling pathway GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway GO:0030514: negative regulation of BMP signaling pathway GO:0031589: cell-substrate adhesion GO:0034616: response to laminar fluid shear stress GO:0043627: response to estrogen stimulus GO:0060394: negative regulation of pathway-restricted SMAD protein phosphorylation GO:0005829: cytosol GO:0005634: nucleus GO:0005737: cytoplasm GO:0005667: transcription factor complex GO:0005515: protein binding GO:0003682: chromatin binding GO:0003700: sequence-specific DNA binding transcription factor activity GO:0030617: transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity GO:0046872: metal ion binding GO:0044212: transcription regulatory region DNA binding GO:0031625: ubiquitin protein ligase binding GO:0034713: type I transforming growth factor beta receptor binding GO:0070410: co-SMAD binding GO:0070411: I-SMAD binding GO:0070412: R-SMAD binding GO:0070698: type I activin receptor binding |
KEGG pathways |
4144: Endocytosis 4350: TGF-beta signaling pathway |
PMID | Title | Tumor | Value |
---|---|---|---|
15174116 | Differential expression of osteogenic factors associated with osteoinductivity of human osteosarcoma cell lines. | no | no |
title | all | all |