Results for SMAD6

General Information

Gene ID 4091
Gene Symbol SMAD6
Gene Name SMAD family member 6
Gene Type protein-coding
Cytoband 15q21-q22
Ensembl ID ENSG00000137834
#miR regulators 7
Omim ID 602931 614823
Gene ontology GO:0001657: ureteric bud development
GO:0006351: transcription, DNA-dependent
GO:0006955: immune response
GO:0007179: transforming growth factor beta receptor signaling pathway
GO:0007352: zygotic specification of dorsal/ventral axis
GO:0043066: negative regulation of apoptotic process
GO:0008285: negative regulation of cell proliferation
GO:0010991: negative regulation of SMAD protein complex assembly
GO:0030509: BMP signaling pathway
GO:0030512: negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514: negative regulation of BMP signaling pathway
GO:0031589: cell-substrate adhesion
GO:0034616: response to laminar fluid shear stress
GO:0043627: response to estrogen stimulus
GO:0060394: negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0005829: cytosol
GO:0005634: nucleus
GO:0005737: cytoplasm
GO:0005667: transcription factor complex
GO:0005515: protein binding
GO:0003682: chromatin binding
GO:0003700: sequence-specific DNA binding transcription factor activity
GO:0030617: transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
GO:0046872: metal ion binding
GO:0044212: transcription regulatory region DNA binding
GO:0031625: ubiquitin protein ligase binding
GO:0034713: type I transforming growth factor beta receptor binding
GO:0070410: co-SMAD binding
GO:0070411: I-SMAD binding
GO:0070412: R-SMAD binding
GO:0070698: type I activin receptor binding
KEGG pathways 4144: Endocytosis
4350: TGF-beta signaling pathway

PubMed abstracts associated with SMAD6

PMID Title Tumor Value
15174116 Differential expression of osteogenic factors associated with osteoinductivity of human osteosarcoma cell lines. no no
title all all